GC IsoLink II IRMS System highlights

• Unique and fully automated combustion and high-temperature conversion unit for compound-specific analysis of ¹³C, ¹⁵N, ¹⁸O, and ²H
• Sharp peak shape and higher sensitivity by true capillary design
• The ultimate level of performance and versatility in GC-IRMS, including the hyphenation with a quadrupole MS
• Driven by Thermo Scientific™ Qtegra™ ISDS Software

Boost laboratory efficiency
The TRACE 1610 GC is the latest technological breakthrough conceived to maximize uptime and profitability. The TRACE 1610 GC features user-installable, plug-in Thermo Scientific™ iConnect™ Injector and Detector Modules, enabling easy cable- and tubing-free connections.

• Easily adapt the GC system configuration to your needs in minutes without special tools or training requirements with iConnect injector and detector modules
• Simplified troubleshooting operations through quick replacement of iConnect injector and detector modules, without the need for service calls
• Make capillary column installation quick and safe through tool-free Thermo Scientific™ iConnect Column Lock connectors
• Enhance operability by using the multi-functional icon-based touch screen ideal for local instrument control and method development
• Reduce operational costs with a GC system that allows the use of standard consumables
• Save energy with low thermal mass and a quick start-up

Combustion and High Temperature Conversion in parallel
The GC IsoLink II System offers a fully automated switch between the combustion and the High Temperature Conversion as the two heaters are mounted in parallel. Dead volume-free switching technology is driven by the Qtegra ISDS Software, ensuring that the optimal conditions of the reactor in standby are maintained without any loss in the GC-IRMS sensitivity.

• The combustion reactor (operating at 1,000 °C) provides optimal reactor conditions for achieving both complete oxidation and reduction, allowing the use of a single reactor for quantitative ¹³C and ¹⁵N analysis
• Quantitative high-temperature conversion at 1,420 °C is applied for hydrogen analysis and at 1,280 °C for oxygen isotope analysis

Capillary reactor design and connectivity
The capillary design of the reactors maintains high resolution and enables maximal separation of constituent components of complex mixtures. A deactivated capillary is attached to the reactors with a capillary solder joint, eliminating any risk of leakage at reactor entrance. The reactors supplied with the instrument can be easily connected with the Micro Channel Device (MCD), an all-metal-sealed GC connection with Ag-ferrules allow high-temperature GC applications. The MCD is easy to install and already leak-free when finger-tight. No wrench required.

Sample injection flexibility
The GC IsoLink II IRMS System can be operated using automation capabilities of Thermo Scientific™ TriPlus™ RSH SMART Autosampler or Thermo Scientific™ AI/AS 1610 Liquid Autosampler.

• The TriPlus RSH SMART Autosampler offers exceptional precision, flexibility, and productivity in robotic sample-handling solutions
• The AI/AS 1610 Liquid Autosampler is the best quality-to-price solution for budget-conscious laboratories performing high throughput and QA/QC analysis

Simultaneous GC-MS and IRMS acquisition: GC-MS-IRMS
Hyphenated GC-IRMS/quadrupole MS allows simultaneous high-performance isotope ratio analysis, structural information, and identification of individual GC compounds from a single injection. The connection of a Thermo Scientific quadrupole MS to the TRACE 1610 GC in the GC IsoLink II System can be easily achieved by using the standard GC-MS transfer line. The choice of quadrupole MS systems, which couple to GC IsoLink II IRMS System includes:

• Thermo Scientific™ ISQ™ 7610 Single Quadrupole GC-MS Systems
• Thermo Scientific™ TSQ™ 9610 Triple Quadrupole GC-MS/MS Systems
• Thermo Scientific™ Orbitrap™ Exploris™ GC 240 MS System

Smart workflows driven by Qtegra ISDS Software
The GC IsoLink II IRMS System is driven by Qtegra ISDS Software, featuring integration with Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) capabilities. The layered approach for data visualization, online data evaluation and tailored data reports offers full control and confidence from sample to result.