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Cetirizine dihydrochloride, 99+%, Thermo Scientific Chemicals
Catalog number: J63549.09
10 g, Each
Thermo Scientific Chemicals
Cetirizine dihydrochloride, 99+%, Thermo Scientific Chemicals
Catalog number: J63549.09
10 g, Each
Quantity
Catalog number: J63549.09
also known as J63549-09
Price (EUR)
207,90 Online price
231,00
Each
Quantity
-
Chemical Identifiers
CAS
83881-52-1
IUPAC Name
dihydrogen 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid dichloride
Molecular Formula
C21H27Cl3N2O3
InChI Key
PGLIUCLTXOYQMV-UHFFFAOYNA-N
SMILES
[H+].[H+].[Cl-].[Cl-].OC(=O)COCCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=C(Cl)C=C1
Specifications
Specification SheetForm
Powder or crystalline powder
Appearance (Color)
White to pale cream
Assay from Supplier's CofA
≥99.0% (HPLC)
pH
1.20-1.80 (5.0% solution in water)
Description
Cetirizine dihydrochloride is used as a Histamine H-1 receptor antagonist, antihistaminic, piperazines. Inhibits activation of eosinophils and neutrophils. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Cetirizine dihydrochloride is used as a Histamine H-1 receptor antagonist, antihistaminic, piperazines. Inhibits activation of eosinophils and neutrophils. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.
Solubility
Soluble in water, DMSO, ethanol, and methanol.
Notes
Keep container tightly closed. Store away from oxidizing agents.
Cetirizine dihydrochloride is used as a Histamine H-1 receptor antagonist, antihistaminic, piperazines. Inhibits activation of eosinophils and neutrophils. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.
Solubility
Soluble in water, DMSO, ethanol, and methanol.
Notes
Keep container tightly closed. Store away from oxidizing agents.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Label Elements
Signal Word
Warning
Hazard Statements
H302 - Harmful if swallowed
Precautionary Statements
P264 - Wash face, hands and any exposed skin thoroughly after handling
P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P312 - Call a POISON CENTER or doctor if you feel unwell