Thermo Scientific Chemicals

N,N-Dimethylformamide di-tert-butyl Acetal, tech. 90%, Thermo Scientific Chemicals

Catalog number: L00431.06
5 g, Each
Thermo Scientific Chemicals

N,N-Dimethylformamide di-tert-butyl Acetal, tech. 90%, Thermo Scientific Chemicals

Catalog number: L00431.06
5 g, Each
Quantity
Catalog number: L00431.06
also known as L00431-06
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
36805-97-7
IUPAC Name
[bis(tert-butoxy)methyl]dimethylazanium
Molecular Formula
C11H26NO2
InChI Key
DBNQIOANXZVWIP-UHFFFAOYSA-O
SMILES
C[NH+](C)C(OC(C)(C)C)OC(C)(C)C
Form
Liquid
Identification (FTIR)
Conforms
Appearance (Color)
Clear colorless to pale yellow
Assay (GC)
≥88.0%
Refractive Index
1.4060-1.4150 @ 20?C

Description

N,N-Dimethylformamide di-tert-butyl acetal is used as a reagent in the synthesis of (S)-2-(1-tert-butoxycarbonyl-2-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenyl}ethylamino)benzoic acid methyl ester, 3-O-tert-butylmorphine, tert-butylesters of pyrrole and indolecarboxylic acids. Further, it is used in the preparation of indolizines by intermolecular cyclization of picolinium salts.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,N-Dimethylformamide di-tert-butyl acetal is used as a reagent in the synthesis of (S)-2-(1-tert-butoxycarbonyl-2-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenyl}ethylamino)benzoic acid methyl ester, 3-O-tert-butylmorphine, tert-butylesters of pyrrole and indolecarboxylic acids. Further, it is used in the preparation of indolizines by intermolecular cyclization of picolinium salts.

Solubility
Miscible with toluene and benzene.

Notes
Moisture sensitive. Incompatible with strong oxidizing agents and acids.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Flammable liquids
    Category 3
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Specific target organ toxicity - (single exposure)
    Category 3
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H315 - Causes skin irritation

    H319 - Causes serious eye irritation

    H335 - May cause respiratory irritation

    Physical Hazards

    H226 - Flammable liquid and vapor

    Precautionary Statements

    P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking

    P264 - Wash face, hands and any exposed skin thoroughly after handling

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower

    P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

    P312 - Call a POISON CENTER or doctor if you feel unwell

    P332 + P313 - If skin irritation occurs: Get medical advice/attention

    P337 + P313 - If eye irritation persists: Get medical advice/attention