Thermo Scientific Chemicals

4-Hydroxy-1-methylpiperidine, 98%, Thermo Scientific Chemicals

Catalog number: L06415.22
100 g, Each
Thermo Scientific Chemicals

4-Hydroxy-1-methylpiperidine, 98%, Thermo Scientific Chemicals

Catalog number: L06415.22
100 g, Each
Quantity
Catalog number: L06415.22
also known as L06415-22
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
106-52-5
IUPAC Name
1-methylpiperidin-4-ol
Molecular Formula
C6H13NO
InChI Key
BAUWRHPMUVYFOD-UHFFFAOYSA-N
SMILES
CN1CCC(O)CC1
Form
Liquid as melt
Refractive Index
1.4760-1.4810 as melt
Appearance (Color)
Clear colorless to brown
Assay (GC)
≥97.5%

Description

4-Hydroxy-1-methylpiperidine is used as reactant for optimization of Novobiocin scaffold to product antitumor agents, substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis. It is also used as a reactant in the synthesis of CaMKII, VEGFR and FGFR kinase inhibitors and Phosphoinositide-3-kinase, Protein lysine methyltransferase G9a inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Hydroxy-1-methylpiperidine is used as reactant for optimization of Novobiocin scaffold to product antitumor agents, substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis. It is also used as a reactant in the synthesis of CaMKII, VEGFR and FGFR kinase inhibitors and Phosphoinositide-3-kinase, Protein lysine methyltransferase G9a inhibitors.

Solubility
Soluble in water.

Notes
Hygroscopic. Store under dry inert gas. Store away from moisture and oxidizing agents. Incompatible with water and oxidizing agents. Store at 4°C.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Specific target organ toxicity - (single exposure)
    Category 3
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H315 - Causes skin irritation

    H319 - Causes serious eye irritation

    H335 - May cause respiratory irritation

    Precautionary Statements

    P261 - Avoid breathing dust/fume/gas/mist/vapors/spray

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing