Thermo Scientific Chemicals

1-(2-Aminophenyl)pyrrole, 98+%, Thermo Scientific Chemicals

Catalog number: L06887.03
1 g, Each
Thermo Scientific Chemicals

1-(2-Aminophenyl)pyrrole, 98+%, Thermo Scientific Chemicals

Catalog number: L06887.03
1 g, Each
Quantity
Catalog number: L06887.03
also known as L06887-03
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
6025-60-1
IUPAC Name
2-(1H-pyrrol-1-yl)aniline
Molecular Formula
C10H10N2
InChI Key
GDMZHPUPLWQIBD-UHFFFAOYSA-N
SMILES
NC1=CC=CC=C1N1C=CC=C1
Form
Crystals or powder or crystalline powder
Identification (FTIR)
Conforms
Appearance (Color)
White to cream to pale brown or pale yellow
Assay (GC)
≥98.0%
Melting Point (clear melt)
93.5-99.5?C

Description

1-(2-Aminophenyl)pyrrole is used in the synthesis of 4-substituted pyrrolo[1,2-a]quinoxaline derivatives. It participates in Pt(IV)-catalyzed hydroamination triggered cyclization reaction to yield fused pyrrolo [1,2-a] quinoxalines. It is also used as primary and secondary intermediates. They act as antileishmanial agents.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(2-Aminophenyl)pyrrole is used in the synthesis of 4-substituted pyrrolo[1,2-a]quinoxaline derivatives. It participates in Pt(IV)-catalyzed hydroamination triggered cyclization reaction to yield fused pyrrolo [1,2-a] quinoxalines. It is also used as primary and secondary intermediates. They act as antileishmanial agents.

Solubility
Insoluble in water.

Notes
Incompatible materials are oxidizing agents, acids, Acid chlorides, Acid anhydrides, Chloroformates. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Acute oral toxicity
    Category 4
    Acute dermal toxicity
    Category 4
    Acute Inhalation Toxicity - Dusts and Mists
    Category 4
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Specific target organ toxicity - (single exposure)
    Category 3
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H302 + H312 + H332 - Harmful if swallowed, in contact with skin or if inhaled

    H315 - Causes skin irritation

    H319 - Causes serious eye irritation

    H335 - May cause respiratory irritation

    Precautionary Statements

    P261 - Avoid breathing dust/fume/gas/mist/vapors/spray

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P301 + P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell

    P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water