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2-Cyanoethyl diisopropylchlorophosphoramidite, 95%, Thermo Scientific Chemicals
Catalog number: L18575.03
1 g, Each
Thermo Scientific Chemicals
2-Cyanoethyl diisopropylchlorophosphoramidite, 95%, Thermo Scientific Chemicals
Catalog number: L18575.03
1 g, Each
Quantity
Catalog number: L18575.03
also known as L18575-03
Price (EUR)
101,70 Online price
113,00
Each
Quantity
-
Chemical Identifiers
CAS
89992-70-1
IUPAC Name
3-({[bis(propan-2-yl)amino](chloro)phosphanyl}oxy)propanenitrile
Molecular Formula
C9H18ClN2OP
InChI Key
QWTBDIBOOIAZEF-UHFFFAOYNA-N
SMILES
CC(C)N(C(C)C)P(Cl)OCCC#N
Specifications
Specification SheetForm
Liquid
Appearance (Color)
Clear to turbid or hazy colorless to yellow
Assay from Supplier's CofA
≥94.0%
Description
2-Cyanoethyl diisopropylchlorophosphoramidite is a useful intermediate in organic synthesis. It acts as a protecting reagent in DNA synthesis. It is involved in the selective monophosphorylation of carbohydrates and nucleosides. It plays an essential role in the conversion of protected ribonucleosides to phosphoramidites. It is also utilized as phosphitylating reagent for 3'-hydroxyl groups in the synthesis of oligodeoxyribonucleotides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Cyanoethyl diisopropylchlorophosphoramidite is a useful intermediate in organic synthesis. It acts as a protecting reagent in DNA synthesis. It is involved in the selective monophosphorylation of carbohydrates and nucleosides. It plays an essential role in the conversion of protected ribonucleosides to phosphoramidites. It is also utilized as phosphitylating reagent for 3′-hydroxyl groups in the synthesis of oligodeoxyribonucleotides.
Solubility
Miscible with chloroform and dichloromethane.
Notes
Reacts violently with water. Incompatible with alcohols and strong bases.
2-Cyanoethyl diisopropylchlorophosphoramidite is a useful intermediate in organic synthesis. It acts as a protecting reagent in DNA synthesis. It is involved in the selective monophosphorylation of carbohydrates and nucleosides. It plays an essential role in the conversion of protected ribonucleosides to phosphoramidites. It is also utilized as phosphitylating reagent for 3′-hydroxyl groups in the synthesis of oligodeoxyribonucleotides.
Solubility
Miscible with chloroform and dichloromethane.
Notes
Reacts violently with water. Incompatible with alcohols and strong bases.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Pyrophoric liquids
Category 1
Skin Corrosion/Irritation
Category 1
Serious Eye Damage/Eye Irritation
Category 1
Label Elements
Signal Word
Danger
Hazard Statements
H314 - Causes severe skin burns and eye damage
Physical hazards
H250 - Catches fire spontaneously if exposed to air
Precautionary Statements
P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking
P231 + P232 - Handle and store contents under inert gas. Protect from moisture
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P302 + P334 - IF ON SKIN: Immerse in cool water or wrap in wet bandages
P310 - Immediately call a POISON CENTER or doctor/physician
P402 + P404 - Store in a dry place. Store in a closed container