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Cinchonidine, 98.5-101%
Catalog number: 110330250
25 g, Each
Thermo Scientific Chemicals
Cinchonidine, 98.5-101%
Catalog number: 110330250
25 g, Each
Quantity
Catalog number: 110330250
Price (EUR)
62,28 Online price
69,20
Each
Quantity
-
Chemical Identifiers
CAS
485-71-2
IUPAC Name
{5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl}(quinolin-4-yl)methanol
Molecular Formula
C19H22N2O
InChI Key
KMPWYEUPVWOPIM-UHFFFAOYNA-N
SMILES
OC(C1CC2CCN1CC2C=C)C1=C2C=CC=CC2=NC=C1
Specifications
Specification SheetAppearance (Form)
Crystalline powder
Melting point
>=200°C
Titration with HClO4
98.5 to 101.0 % (On dried substance)
Specific optical rotation
-105° to -115° (20°C, 589 nm) (c=1, EtOH)
Infrared spectrum
Conforms
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
Cinchonidine is an alkaloid naturally occurring in the bark of Cinchona strubs that has activity against Plasmodium spp
Cinchonidine is a diastereoisomer of cinchonine and can be used to promote chirality in asymmetric or enantioselective synthesis of organic compounds
Applications
Cinchonidine has been used as a starting material in the synthesis of anti-malarial cinchona alkaloid conjugates
Has been shown to potently induce γ-globin mRNA and fetal hemoglobin in erythroid progenitor cells and may be useful in preclinical studies of β-thalassemia
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Skin Sensitization
Category 1
Label Elements
Signal Word
Warning
Hazard Statements
H302 - Harmful if swallowed
H317 - May cause an allergic skin reaction
Precautionary Statements
P301 + P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water