Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
General Information
• Nitrilotriacetic acid, trisodium salt, monohydrate is considered to be a nongenotoxic compound with carcinogenic activity
• This compound inhibits gap-junctional communication between Chinese hamster lung fibroblasts
Applications
• Nitrilotriacetic acid trisodium salt monohydrate is commonly used in laboratory experiments due to its capacity to induce the tumorigenic process
• It has been used in in vivo experiments as an inducer of bladder and kidney tumors in animal models
• It is used as a chelating agent, which forms coordination compounds with metal ions (chelates)
Literature References
Malcolm, A.; Mills, L. Inhibition of gap-junctional intercellular communication between Chinese hamster lung fibroblasts by di(2-ethylhexyl) phthalate (DEHP) and trisodium nitrilotriacetate monohydrate (NTA). Cell Biology and Toxicology. 1989, 5, 145–153.
Warning
H302 - Harmful if swallowed
H319 - Causes serious eye irritation
H351 - Suspected of causing cancer
P201 - Obtain special instructions before use
P264 - Wash face, hands and any exposed skin thoroughly after handling
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P308 + P313 - IF exposed or concerned: Get medical advice/attention