Vitamin D2, 97+%
Vitamin D2, 97+%
Vitamin D2, 97+%
Thermo Scientific Chemicals

Vitamin D2, 97+%

Vitamin D2, or Ergocalciferol, CAS # 50-14-6, a fat-soluble hormone that is important for calcium and phosphorus absorption and metabolism. | CAS: 50-14-6 | C28H44O | 396.66 g/mol
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5 g
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Glass bottle
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Catalog number 422630050
Price (EUR)
171,70
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207,00
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Quantity:
5 g
Packaging:
Glass bottle
Request bulk or custom format
Price (EUR)
171,70
Online Exclusive
207,00
Save 35,30 (17%)
Each
Add to cart
Chemical Identifiers
CAS50-14-6
IUPAC Name(1S,3E)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol
Molecular FormulaC28H44O
InChI KeyMECHNRXZTMCUDQ-VLOQVYPSSA-N
SMILESCC(C)[C@@H](C)\C=C\[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1/C[C@@H](O)CCC1=C
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to light yellow
Appearance (Form)Powder or crystals
Melting point113°C to 119°C
HPLC97.0 to 103.0 %
Specific optical rotation+100° to +106° (20°C, 589 nm) (c=1,5; EtOH)
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Vitamin D2 (ergocalciferol) is a form of vitamin D, a fat-soluble hormone found in food sources
  • Vitamin D is important for calcium and phosphorus homeostasis, and can play a role in many biological processes including cell growth
  • Vitamin D2 has a lower binding affinity than Vitamin D3 for vitamin D binding protein

Applications

  • Research studies show that Vitamin D2 treatment in rats inhibits bladder tumor promotion
  • Studies show that the treatment of lung carcinoma cells with vitamin D2 in vitro resulted in increased ACE2 protein levels
  • Vitamin D2 has been seen to interfere with prion protein oligomerization in vitro
RUO – Research Use Only

General References:

  1. Yazawa, Y., et al., 2000. Antitumor promoting effect of an active component of Polyporus, ergosterol and related compounds on rat urinary bladder carcinogenesis in a short-term test with concanavalin A. Biological & pharmaceutical bulletin. 23(11): 1298-302.
  2. Bártová, E.; Legartová, S.; Krejčí, J.; Arcidiacono, O.A. Cell differentiation and aging accompanied by depletion of the ACE2 protein. Aging (Albany NY). 2020, 12(22), 22495-22508.
  3. Suenaga, M.; Hiramoto, Y.; Matsunaga, Y. Vitamin D 2 interacts with Human PrP(c) (90-231) and breaks PrP(c) oligomerization in vitro. Prion. 2013, 7(4), 312-8.
  4. Soto-Dávila, M.; Valderrama, K.; Inkpen, S.M.; Hall, J.R.; Rise, M.L.; Santander, J. Effects of Vitamin D2 (Ergocalciferol) and D3 (Cholecalciferol) on Atlantic Salmon (Salmo salar) Primary Macrophage Immune Response to Aeromonas salmonicida subsp. salmonicida Infection. Front Immunol. 2020, 10, 3011.

Documents & Downloads

Certificates

Safety Data Sheets

Safety and Handling

Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 3
Acute dermal toxicity
Category 3
Acute Inhalation Toxicity - Dusts and Mists
Category 2
Specific target organ toxicity - (repeated exposure)
Category 1
Label Elements
Signal Word

Danger

Hazard Statements

H301 + H311 - Toxic if swallowed or in contact with skin

H330 - Fatal if inhaled

H372 - Causes damage to organs through prolonged or repeated exposure if swallowed

Precautionary Statements

P260 - Do not breathe dust/fume/gas/mist/vapors/spray

P280 - Wear protective gloves/protective clothing/eye protection/face protection

P302 + P350 - IF ON SKIN: Gently wash with plenty of soap and water

P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing

P310 - Immediately call a POISON CENTER or doctor/physician

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