3-Chloropropiophenone, 96%, Thermo Scientific Chemicals
3-Chloropropiophenone, 96%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

3-Chloropropiophenone, 96%, Thermo Scientific Chemicals

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50 g
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100 g
Catalog number A12290.18
also known as A12290-18
Price (EUR)/ Each
145,96
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164.00 
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Quantity:
50 g
Request bulk or custom format
Price (EUR)/ Each
145,96
Online exclusive
164.00 
Save 18,04 (11%)
Add to cart
3-Chloropropiophenone, 96%, Thermo Scientific Chemicals
Catalog numberA12290.18
Price (EUR)/ Each
145,96
Online exclusive
164.00 
Save 18,04 (11%)
-
Add to cart
Chemical Identifiers
CAS936-59-4
IUPAC Name3-chloro-1-phenylpropan-1-one
Molecular FormulaC9H9ClO
InChI KeyKTJRGPZVSKWRTJ-UHFFFAOYSA-N
SMILESClCCC(=O)C1=CC=CC=C1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to pale cream to pale brown
Melting Point (clear melt)42.0-52.0?C
FormCrystals or powder or crystalline powder or fused solid
Assay (GC)≥95.0%
3-Chloropropiophenone was used in the asymmetric reduction of (S)-3-chloro-1-phenylpropanol using preheated Candida utilis cells immobilized in calcium alginate gel beads. It was also used in the synthesis of (R)-3-chloro-1-phenyl-1-propanol via asymmetric reduction using in-situ generated oxazaborolidine catalyst derived from (S)-α,α-diphenylprolinol. It is a precursor of phenyl vinyl ketone.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Chloropropiophenone was used in the asymmetric reduction of (S)-3-chloro-1-phenylpropanol using preheated Candida utilis cells immobilized in calcium alginate gel beads. It was also used in the synthesis of (R)-3-chloro-1-phenyl-1-propanol via asymmetric reduction using in-situ generated oxazaborolidine catalyst derived from (S)-α,α-diphenylprolinol. It is a precursor of phenyl vinyl ketone.

Solubility
Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Yang Gen-Sheng; Xu Jiang-Yan; Ou Zhi-Min; Yao Shan-Jing. Asymmetric reduction of (S)-3-chloro-1-phenylpropanol from 3-chloropropiophenone by preheated immobilized Candida utilis. Biotechnology Letters. 2009, 31 (12), 1879-1883.
  2. Yu-Chang Liu; Yan Liu; Zhong-Liu Wu. Synthesis of enantiopure glycidol derivatives via a one-pot two-step enzymatic cascade. Organic & Biomolecular Chemistry. 2015, 13 (7), 2146-2152.
  3. Precursor of phenyl vinyl ketone.