Thermo Scientific Chemicals

Iodoacetic acid, 97+%, Thermo Scientific Chemicals

Catalog number: A12410.22
100 g, Each
Thermo Scientific Chemicals

Iodoacetic acid, 97+%, Thermo Scientific Chemicals

Catalog number: A12410.22
100 g, Each
Quantity
Catalog number: A12410.22
also known as A12410-22
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
64-69-7
IUPAC Name
2-iodoacetic acid
Molecular Formula
C2H3IO2
InChI Key
JDNTWHVOXJZDSN-UHFFFAOYSA-N
SMILES
OC(=O)CI
Assay (Aqueous acid-base Titration)
≥97.0 to ≤103.0%
Melting Point (clear melt)
74-85?C
Appearance (Color)
White to yellow to orange-brown or pale cream to cream
Form
Powder or crystalline powder or crystals or flakes
Identification (FTIR)
Conforms

Description

Iodoacetic acid is used as a reagent for the modification of sulfhydryl groups in organic synthesis. It reacts with cysteine moiety in proteins to prevent the re-formation of disulfide bonds during protein sequencing. It is also used as a general reagent in acylation reactions as well as in glycopeptide synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Iodoacetic acid is used as a reagent for the modification of sulfhydryl groups in organic synthesis. It reacts with cysteine moiety in proteins to prevent the re-formation of disulfide bonds during protein sequencing. It is also used as a general reagent in acylation reactions as well as in glycopeptide synthesis.

Solubility
Soluble in water, alcohol and ethanol. Slightly soluble in ether and chloroform.

Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, bases and strong reducing agents.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Acute oral toxicity
    Category 3
    Skin Corrosion/Irritation
    Category 1
    Serious Eye Damage/Eye Irritation
    Category 1
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H301 - Toxic if swallowed

    H314 - Causes severe skin burns and eye damage

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting

    P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P310 - Immediately call a POISON CENTER or doctor/physician