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1-(Trimethylsilyl)imidazole, 97%, Thermo Scientific Chemicals
Catalog number: A12512.22
100 g, Each
Thermo Scientific Chemicals
1-(Trimethylsilyl)imidazole, 97%, Thermo Scientific Chemicals
Catalog number: A12512.22
100 g, Each
Quantity
Catalog number: A12512.22
also known as A12512-22
Price (EUR)
133,20 Online price
148,00
Each
Quantity
-
Chemical Identifiers
CAS
18156-74-6
IUPAC Name
1-(trimethylsilyl)-1H-imidazole
Molecular Formula
C6H12N2Si
InChI Key
YKFRUJSEPGHZFJ-UHFFFAOYSA-N
SMILES
C[Si](C)(C)N1C=CN=C1
Specifications
Specification SheetAppearance (Color)
Clear colorless to pale yellow
Assay (GC)
≥96.0%
Identification (FTIR)
Conforms
Refractive Index
1.4740-1.4790 @ 20?C
Form
Liquid
Description
1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.
Solubility
Miscible with most common organic solvents. It decomposes in water.
Notes
Moisture and light sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong acids.
1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.
Solubility
Miscible with most common organic solvents. It decomposes in water.
Notes
Moisture and light sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong acids.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Flammable liquids
Category 2
Acute oral toxicity
Category 4
Skin Corrosion/Irritation
Category 1
Serious Eye Damage/Eye Irritation
Category 1
Reproductive Toxicity
Category 1B
Chronic aquatic toxicity
Category 1
Label Elements
Signal Word
Danger
Hazard Statements
H302 - Harmful if swallowed
H314 - Causes severe skin burns and eye damage
H360D - May damage the unborn child
H410 - Very toxic to aquatic life with long lasting effects
Physical Hazards
H225 - Highly flammable liquid and vapor
Precautionary Statements
P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P310 - Immediately call a POISON CENTER or doctor/physician
Additional EU labelling
Restricted to professional users