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tert-Butyldimethylchlorosilane, 97%, Thermo Scientific Chemicals
Catalog number: A13064.14
25 g, Each
Thermo Scientific Chemicals
tert-Butyldimethylchlorosilane, 97%, Thermo Scientific Chemicals
Catalog number: A13064.14
25 g, Each
Quantity
Catalog number: A13064.14
also known as A13064-14
Price (EUR)
126,90 Online price
141,00
Each
Quantity
-
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Chemical Identifiers
CAS
18162-48-6
IUPAC Name
tert-butyl(chloro)dimethylsilane
Molecular Formula
C6H15ClSi
InChI Key
BCNZYOJHNLTNEZ-UHFFFAOYSA-N
SMILES
CC(C)(C)[Si](C)(C)Cl
Specifications
Specification SheetMelting Point (clear melt)
84.0-94.0°C (non-U.S. specification)
Identification (FTIR)
Conforms (non-U.S. specification)
Appearance (Color)
Colorless to white
Form
Crystals or powder or crystalline powder or lumps or fused solid
Assay (GC)
≥96.0%
Description
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.
Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.
Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.
Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.
Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Flammable solids
Category 2
Skin Corrosion/Irritation
Category 1
Serious Eye Damage/Eye Irritation
Category 1
Chronic aquatic toxicity
Category 2
Label Elements
Signal Word
Danger
Hazard Statements
H314 - Causes severe skin burns and eye damage
H411 - Toxic to aquatic life with long lasting effects
Physical Hazards
H228 - Flammable solid
Precautionary Statements
P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P310 - Immediately call a POISON CENTER or doctor/physician