Thermo Scientific™

Di-n-butyl ether, 99%, Thermo Scientific Chemicals

Catalog number: A16305.AP
500 mL, Each
Thermo Scientific™

Di-n-butyl ether, 99%, Thermo Scientific Chemicals

Catalog number: A16305.AP
500 mL, Each
Quantity
Catalog number: A16305.AP
also known as A16305-AP
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
142-96-1
IUPAC Name
1-butoxybutane
Molecular Formula
C8H18O
InChI Key
DURPTKYDGMDSBL-UHFFFAOYSA-N
SMILES
CCCCOCCCC
Appearance (Color)
Clear colorless
Form
Liquid
Assay (GC)
≥98.5%
Refractive Index
1.3970-1.4010 @ 20°C
Water Content
≤200 ppm

Description

Di-n-butyl ether is used as a solvent for Grignard, Witting and alkyl lithium reactions. It is also used as a solvent for oils and fats and some natural and synthetic resins. It is considered as a replacement for terathydofuran in organic synthesis due to its less water and peroxide and high boiling point. In the pharmaceutical industry, it is used in the manufacturing process of active pharmaceutical ingredient such as procarbazine and cefaclor. In addition to this, it is used as an important solvent for the application of the coating.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Di-n-butyl ether is used as a solvent for Grignard, Witting and alkyl lithium reactions. It is also used as a solvent for oils and fats and some natural and synthetic resins. It is considered as a replacement for terathydofuran in organic synthesis due to its less water and peroxide and high boiling point. In the pharmaceutical industry, it is used in the manufacturing process of active pharmaceutical ingredient such as procarbazine and cefaclor. In addition to this, it is used as an important solvent for the application of the coating.

Solubility
Miscible with alcohol, ether and acetone. Immiscible with water.

Notes
Air and light sensitive. Incompatible with oxidizing agents and strong acids.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Flammable liquids
    Category 3
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Specific target organ toxicity - (single exposure)
    Category 3
    Chronic aquatic toxicity
    Category 3
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H315 - Causes skin irritation

    H319 - Causes serious eye irritation

    H335 - May cause respiratory irritation

    H412 - Harmful to aquatic life with long lasting effects

    Physical Hazards

    H226 - Flammable liquid and vapor

    Precautionary Statements

    P261 - Avoid breathing dust/fume/gas/mist/vapors/spray

    P273 - Avoid release to the environment

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking