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Trichloromethyl chloroformate, 98%, Thermo Scientific Chemicals
Catalog number: A17444.30
250 g, Each
Thermo Scientific Chemicals
Trichloromethyl chloroformate, 98%, Thermo Scientific Chemicals
Catalog number: A17444.30
250 g, Each
Quantity
Catalog number: A17444.30
also known as A17444-30
Price (EUR)
388,80 Online price
432,00
Each
Quantity
-
Chemical Identifiers
CAS
503-38-8
IUPAC Name
trichloromethyl carbonochloridate
Molecular Formula
C2Cl4O2
InChI Key
HCUYBXPSSCRKRF-UHFFFAOYSA-N
SMILES
ClC(=O)OC(Cl)(Cl)Cl
Specifications
Specification SheetAppearance (Color)
Clear colorless
Assay (Titration ex Chloride)
≥97.5 to ≤102.5%
Refractive Index
1.4560-1.4600 @ 20?C
Identification (FTIR)
Conforms
Form
Liquid
Description
Trichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Trichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.
Solubility
Miscible with ethanol, ether and benzene. Immiscible with water.
Notes
Special handling precautions required. View MSDS prior to purchase. MSDS are available online at www.alfa.comStore in a cool place. Light and heat sensitive. Incompatible with strong oxidizing agents and bases.
Trichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.
Solubility
Miscible with ethanol, ether and benzene. Immiscible with water.
Notes
Special handling precautions required. View MSDS prior to purchase. MSDS are available online at www.alfa.comStore in a cool place. Light and heat sensitive. Incompatible with strong oxidizing agents and bases.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 2
Acute Inhalation Toxicity - Vapors
Category 1
Skin Corrosion/Irritation
Category 1
Serious Eye Damage/Eye Irritation
Category 1
Label Elements
Signal Word
Danger
Hazard Statements
H300 + H330 - Fatal if swallowed or if inhaled
H314 - Causes severe skin burns and eye damage
Precautionary Statements
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower
P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P310 - Immediately call a POISON CENTER or doctor/physician