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Dexamethasone, 98%, Thermo Scientific Chemicals
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Catalog number A17590.14
also known as A17590-14
Price (EUR)/ Each
899,79
Online exclusive
1011.00 Save 111,21 (11%)
-
Quantity:
25 g
Price (EUR)/ Each
899,79
Online exclusive
1011.00 Save 111,21 (11%)
Dexamethasone, 98%, Thermo Scientific Chemicals
Catalog numberA17590.14
Price (EUR)/ Each
899,79
Online exclusive
1011.00 Save 111,21 (11%)
-
Chemical Identifiers
CAS50-02-2
IUPAC Name(1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
Molecular FormulaC22H29FO5
InChI KeyUREBDLICKHMUKA-CXSFZGCWSA-N
SMILESC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
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Specifications
Specification Sheet
Specification SheetOptical Rotation77.0 ± 3.0? (C=1 in dioxane)
Appearance (Color)White
Assay (HPLC)≥97.5%
FormPowder
Identification (FTIR)Conforms
Anti-inflammatory glucocorticoidDexamethasone is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide. It is also an anti-inflammatory glucocorticoid.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Anti-inflammatory glucocorticoidDexamethasone is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide. It is also an anti-inflammatory glucocorticoid.
Solubility
Soluble in ethanol and dimethyl sulfoxide. Insoluble in water.
Notes
Store in cool place. Light sensitive. Incompatible with strong oxidizing agents.
Anti-inflammatory glucocorticoidDexamethasone is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide. It is also an anti-inflammatory glucocorticoid.
Solubility
Soluble in ethanol and dimethyl sulfoxide. Insoluble in water.
Notes
Store in cool place. Light sensitive. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Han, L.; Wang, Z.; Lu, X.; Dong, L.; Xie, C.; Wang, K.; Chen, X.; Ding, Y.; Weng, L. Mussel-inspired adhesive and transferable free-standing films by self-assembling dexamethasone encapsulated BSA nanoparticles and vancomycin immobilized oxidized alginate. Colloids Surf., B 2015, 126, 452-458.
- Khataee, A.; Hasanzadeh, A.; Lotfi, R.; Pourata, R.; Joo, S. W. Determination of dexamethasone by flow-injection chemiluminescence method using capped CdS quantum dots. Spectrochim. Acta, Part A 2015, 150 (5), 63-71.