Thermo Scientific™

Phenylacetyl chloride, 98%, Thermo Scientific Chemicals

Catalog number: B24987.36
500 g, Each
Thermo Scientific™

Phenylacetyl chloride, 98%, Thermo Scientific Chemicals

Catalog number: B24987.36
500 g, Each
Quantity
Catalog number: B24987.36
also known as B24987-36
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
103-80-0
IUPAC Name
2-phenylacetyl chloride
Molecular Formula
C8H7ClO
InChI Key
VMZCDNSFRSVYKQ-UHFFFAOYSA-N
SMILES
ClC(=O)CC1=CC=CC=C1
Form
Liquid
Assay (Methyl Ester GC)
≥97.5% (UK sourced material only)
Appearance (Color)
Clear colorless to yellow or pink-red
Assay from Supplier's CofA
≥97.5% (GC) (US sourced material only)
Assay (Titration ex Chloride)
≥97.5 to ≤102,5% (UK sourced material)

Description

Phenylacetyl chloride is used in the preparation of 1,2-diphenyl-ethanone by reaction with iodobenzene using tetrabutylammonium tetrafluoroborate as a phase transfer catalyst. It is widely used in the chemical industry for manufacturing dyes and pharmaceutical products. It plays an important role in the preparation of penicillin. Further, it is used to prepare esters for flavorings.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenylacetyl chloride is used in the preparation of 1,2-diphenyl-ethanone by reaction with iodobenzene using tetrabutylammonium tetrafluoroborate as a phase transfer catalyst. It is widely used in the chemical industry for manufacturing dyes and pharmaceutical products. It plays an important role in the preparation of penicillin. Further, it is used to prepare esters for flavorings.

Solubility
Miscible with alcohol and ether.

Notes
Moisture sensitive. Store in a cool place.Incompatible with amines, most common metals, strong bases and strong oxidizing agents.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Corrosion/Irritation
    Category 1
    Serious Eye Damage/Eye Irritation
    Category 1
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H314 - Causes severe skin burns and eye damage

    EU Specific Hazard Statements

    May form combustible dust concentrations in air

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting

    P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P310 - Immediately call a POISON CENTER or doctor/physician