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Niflumic acid, 99+%, Thermo Scientific Chemicals
Catalog number: J60489.09
10 g, Each
Thermo Scientific Chemicals
Niflumic acid, 99+%, Thermo Scientific Chemicals
Catalog number: J60489.09
10 g, Each
Quantity
Catalog number: J60489.09
also known as J60489-09
Price (EUR)
71,19 Online price
79,10
Each
Quantity
-
Chemical Identifiers
CAS
4394-00-7
IUPAC Name
2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid
Molecular Formula
C13H9F3N2O2
InChI Key
JZFPYUNJRRFVQU-UHFFFAOYSA-N
SMILES
OC(=O)C1=CC=CN=C1NC1=CC=CC(=C1)C(F)(F)F
Specifications
Specification SheetForm
Powder or crystals or crystalline powder
Infrared spectrum
Conforms
Purity
≥99.0%
Description
It is used as a selective Cox-2 inhibitor and GPR35 activator. Also activates human TRPA1 inducibly expressed in HEK293 cells; displays agonist activity at GPR35.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is used as a selective Cox-2 inhibitor and GPR35 activator. Also activates human TRPA1 inducibly expressed in HEK293 cells; displays agonist activity at GPR35.
Solubility
Soluble in ethanol (∼50 mg/ml), acetone (50 mg/ml, Clear to Slightly Hazy, Yellow), methanol (∼50 mg/ml), DMSO (56 mg/ml at 25°C), and acetonitrile (∼50 mg/ml).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Hygroscopic. Keep away fom strong oxidizing agents.
It is used as a selective Cox-2 inhibitor and GPR35 activator. Also activates human TRPA1 inducibly expressed in HEK293 cells; displays agonist activity at GPR35.
Solubility
Soluble in ethanol (∼50 mg/ml), acetone (50 mg/ml, Clear to Slightly Hazy, Yellow), methanol (∼50 mg/ml), DMSO (56 mg/ml at 25°C), and acetonitrile (∼50 mg/ml).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Hygroscopic. Keep away fom strong oxidizing agents.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Acute dermal toxicity
Category 4
Acute Inhalation Toxicity - Dusts and Mists
Category 4
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Specific target organ toxicity - (single exposure)
Category 3
Label Elements
Signal Word
Warning
Hazard Statements
H302 + H312 + H332 - Harmful if swallowed, in contact with skin or if inhaled
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H335 - May cause respiratory irritation
Precautionary Statements
P261 - Avoid breathing dust/fume/gas/mist/vapors/spray
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water