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Cefotaxima, sal sódica, 95 %
Cefotaxime sodium salt, CAS # 64485-93-4, is the sodium salt form of cefotaxime with β-lactamase resistant antibiotic activity.
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| Número de catálogo | Cantidad | Envase |
|---|---|---|
| 454950010 | 1 g | Frasco de vidrio |
| 454950050 | 5 g | Frasco de vidrio |
Número de catálogo 454950010
Precio (EUR)
57,55
キャンペーン価格
67,70Ahorro 10,15 (15%)
Each
-
Cantidad:
1 g
Envase:
Frasco de vidrio
Precio (EUR)
57,55
キャンペーン価格
67,70Ahorro 10,15 (15%)
Each
Identificadores químicos
CAS64485-93-4
IUPAC Namesodium (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Molecular FormulaC16H16N5NaO7S2
InChI KeyAZZMGZXNTDTSME-JUZDKLSSSA-M
SMILES[Na+].CON=C(/C(=O)N[C@H]1[C@H]2SCC(COC(C)=O)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1
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Especificaciones
Hoja de especificaciones
Hoja de especificacionesHPLC>=94 %
pH4.5 to 6.5
Appearance (Color)White to light yellow
Infrared spectrumConforms
Loss on drying=<3.0 % (105°C, 8 hrs)
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Information
• The cefotaxime sodium salt is a - lactamase considered a third-generation cephalosporin with antibiotic and bactericidal activities
• This compound exerts its biological activity by binding to penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall leading to their inactivation. The inactivation of these proteins affects the cross-linking of peptidoglycan chains required for bacterial cell wall strength and rigidity, resulting in the weakening of cell walls and cell lysis.
Applications
• It is an efficient antibacterial compound that acts against gram-negative bacteria, without activity against gram-positive bacteria such as pseudomonas and penicillin-resistant strains of streptococcus pneumonia
• It has been used for plant cell culture and human cell lines in vitro
• Cefotaxime sodium salt has been used in antibiotic susceptibility testing (AST) methods
• Cefotaxime sodium salt is also used to remove bacteria from Ostreococcus tauri cultures
RUO – Research Use Only
Literature References
Ali, M. M.; Gaballa, A. S.; Teleb, S. M. Spectroscopic and thermal investigations of charge-transfer complexes formed between cefotaxime sodium drug and various acceptors. Russ. J. Gen. Chem. 2015, 85 (3), 731-745.
Yin, Y.; Bao, Y.; Gao, Z.; Wang, Z.; Liu, D.; Hao, H.; Wang, Y. Solubility of Cefotaxime Sodium in Ethanol + Water Mixtures under Acetic Acid Conditions. J. Chem. Eng. Data 2014, 59 (6), 1865-1871.
Carmine, A.; Brogden, R.; Heel, R.; Speight, T.; Avery, G. Cefotaxime. A review of its antibacterial activity, pharmacological properties and therapeutic use. Drugs. 1983, 25 (3), 223-289.
Documentos y descargas
Certificados
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Hojas de datos de seguridad
Seguridad y manipulación
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Respiratory Sensitization
Category 1
Skin Sensitization
Category 1
Specific target organ toxicity - (single exposure)
Category 3
Label Elements
Signal Word
Danger
Hazard Statements
H315 - Causes skin irritation
H317 - May cause an allergic skin reaction
H319 - Causes serious eye irritation
H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335 - May cause respiratory irritation
Precautionary Statements
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P312 - Call a POISON CENTER or doctor if you feel unwell