Cloxacilina, sal sódica monohidrato
Cloxacilina, sal sódica monohidrato
Cloxacilina, sal sódica monohidrato
Cloxacilina, sal sódica monohidrato
Thermo Scientific Chemicals

Cloxacilina, sal sódica monohidrato

La sal sódica monohidratada de cloxacilina, n.° de CAS 7081-44-9, es un compuesto que se dirige a bacterias grampositivas y presenta actividad antibacteriana.
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Número de catálogoCantidad
4553000505 g
4553000101 g
Número de catálogo 455300050
Precio (EUR)
157,25
Online Exclusive
190,00
Ahorro 32,75 (17%)
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Cantidad:
5 g
Pedido a granel o personalizado
Precio (EUR)
157,25
Online Exclusive
190,00
Ahorro 32,75 (17%)
Each
Añadir al carro de la compra
Identificadores químicos
CAS7081-44-9
IUPAC Namesodium (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate
Molecular FormulaC19H19ClN3NaO6S
InChI KeyKCUWTKOTPIUBRI-VICXVTCVSA-M
SMILESO.[Na+].CC1=C(C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)C(=NO1)C1=CC=CC=C1Cl
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EspecificacionesSpecification SheetHoja de especificaciones
Appearance (Color)White
Appearance (Form)Crystalline powder
Infrared spectrumConforms
HPLC>=94 %
Water3.0 to 5.0 %
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Descripción general

• La sal sódica monohidratada de cloxacilina es un derivado clorado de oxacilina que muestra actividad antibiótica resistente a la β-lactamasa

•Este compuesto inhibe la última etapa de la síntesis de la pared celular bacteriana mediante la unión a proteínas de unión a la penicilina (PBP), lo que da lugar a lisis celular, mediada por enzimas autolíticas de pared celular bacteriana

Aplicaciones

• La sal sódica monohidratada de cloxacilina se dirige a las bacterias grampositivas y es eficaz contra los estafilococos que producen β-lactamasa

• Actúa in vitro contra estafilococos gramresistentes y gramsensibles a la penicilina, algunos estreptococos y neumococos

• Este compuesto se utiliza comúnmente en estudios in vivo e in vitro como inhibidor de la β-lactamasa AmpC en combinación con antibióticos β-lactámicos

RUO – Research Use Only

Referencias bibliográficas

A New Antibacterial Agent:Sodium Cloxacillin Monohydrate (Tegopen).Journal of the American Medical Association.1966, 195, 569-570.

Harris, P.N.; Ferguson, J.K.Antibiotic therapy for inducible AmpC β-lactamase-producing Gram-negative bacilli: what are the alternatives to carbapenems, quinolones and aminoglycosides?Int J Antimicrob Agents.2012, 40, (4), 297-305.

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Certificados

N.º de loteCertificate TypeDateCatalog Number(s)
A0471165Certificate of Analysis17 may 2025455300010, 455300050
A0445565Certificate of Analysis17 may 2025455300010, 455300050
A0462488Certificate of Analysis01 jul 2024455300010, 455300050
A0452131Certificate of Analysis25 ago 2023455300010, 455300050
A0401730Certificate of Analysis14 dic 2022455300010, 455300050
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Hojas de datos de seguridad

Seguridad y manipulación

Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Respiratory Sensitization
Category 1
Skin Sensitization
Category 1
Specific target organ toxicity - (single exposure)
Category 3
Label Elements
Signal Word

Danger

Hazard Statements

H315 - Causes skin irritation

H317 - May cause an allergic skin reaction

H319 - Causes serious eye irritation

H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335 - May cause respiratory irritation

Precautionary Statements

P280 - Wear protective gloves/protective clothing/eye protection/face protection

P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

P312 - Call a POISON CENTER or doctor if you feel unwell

P332 + P313 - If skin irritation occurs: Get medical advice/attention

P333 + P313 - If skin irritation or rash occurs: Get medical advice/attention

P337 + P313 - If eye irritation persists: Get medical advice/attention

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