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Ceftriaxona, sal sódica hemiheptahidrato
Ceftriaxona, sal sódica hemiheptahidrato
Ceftriaxona, sal sódica hemiheptahidrato
Ceftriaxona, sal sódica hemiheptahidrato
Thermo Scientific Chemicals

Ceftriaxona, sal sódica hemiheptahidrato

La ceftriaxona, n.° de CAS 104376-79-6, la sal sódica hemiheptahidrato, es la sal sódica de la ceftriaxona, un antibiótico beta-lactámico de tercera generación del tipo cefalosporina.
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Número de catálogoCantidad
4554200101 g
4554200505 g
45542025025 g
Número de catálogo 455420010
Precio (EUR)
25,93
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31,30
Ahorro 5,37 (17%)
Each
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Cantidad:
1 g
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Precio (EUR)
25,93
Online Exclusive
31,30
Ahorro 5,37 (17%)
Each
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Identificadores químicos
CAS104376-79-6
IUPAC Nametetrasodium 3-({[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}sulfanyl)-2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-1-ide (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(2-methyl-6-oxido-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate heptahydrate
Molecular FormulaC36H46N16Na4O21S6
InChI KeyRGDBKADCOSIOEV-MAODNAKNSA-J
SMILESO.O.O.O.O.O.O.[Na+].[Na+].[Na+].[Na+].CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(CSC3=NC(=O)C(=O)[N-]N3C)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1.CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(CSC3=NC(=O)C([O-])=NN3C)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1
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EspecificacionesSpecification SheetHoja de especificaciones
Water=<10 %
Appearance (Color)White to light yellow
Infrared spectrumConforms
Appearance (Form)Crystalline powder
HPLC>=94 %
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Descripción general

• La ceftriaxona es la sal sódica de la ceftriaxona, un antibiótico beta-lactámico del tipo cefalosporina que funciona inactivando proteínas de unión a la penicilina

Aplicaciones

• La inactivación de proteínas de unión a la penicilina inhibe la unión cruzada de peptidoglucano y conduce a la destrucción de la pared celular y la lisis posterior

• Presenta actividad antibiótica contra bacterias gramnegativas

RUO – Research Use Only

Referencias bibliográficas

Grégoire, M.; Dailly, E.; Le Turnier, P.; Garot, D.; Guimard, T.; Bernard, L.; Tattevin, P.; Vandamme, Y.M.; Hoff, J.; Lemaitre, F.; Verdier, M.C.; Deslandes, G.; Bellouard, R.; Sébille, V.; Chiffoleau, A.; Boutoille, D.; Navas, D.; Asseray, N. High-Dose Ceftriaxone for Bacterial Meningitis and Optimization of Administration Scheme Based on Nomogram.Antimicrob Agents Chemother.2019, 63(9), e00634-19.

Ross, J.D.C.; Brittain, C.; Cole, M.; Dewsnap, C.; Harding, J.; Hepburn, T.; Jackson, L.; Keogh, M.; Lawrence, T.; Montgomery, A.A.; Roberts, T.E.; Sprange, K.; Tan, W.; Thandi S, White J.; Wilson, J.; Duley, L. G-ToG trial team.Gentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG): a randomised non-inferiority trial.Lancet.2019, 22, 393(10190), 2511-2520.Erratum in:Lancet.2019, Erratum in:Lancet, 394(10205), 1230.

Documentos y descargas

Certificados

Hojas de datos de seguridad

Seguridad y manipulación

Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Respiratory Sensitization
Category 1
Skin Sensitization
Category 1
Specific target organ toxicity - (single exposure)
Category 3
Label Elements
Signal Word

Danger

Hazard Statements

H315 - Causes skin irritation

H317 - May cause an allergic skin reaction

H319 - Causes serious eye irritation

H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335 - May cause respiratory irritation

Precautionary Statements

P280 - Wear protective gloves/protective clothing/eye protection/face protection

P284 - Wear respiratory protection

P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

P312 - Call a POISON CENTER or doctor if you feel unwell

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