Thermo Scientific Chemicals

Estreptomicina, sulfato, reactivo para cultivo celular, Thermo Scientific Chemicals

Número de catálogo: J61299.18
50 g, Each
Thermo Scientific Chemicals

Estreptomicina, sulfato, reactivo para cultivo celular, Thermo Scientific Chemicals

Número de catálogo: J61299.18
50 g, Each
Cantidad
Informational:Con fines informativos:Este producto químico puede requerir que obtengamos información adicional para nuestros registros de cumplimiento normativo y químico. Si es necesario, nos pondremos en contacto con usted para obtener esta información una vez que haya realizado su pedido.
Número de catálogo: J61299.18
también denominado J61299-18
Precio (EUR)
Cantidad
-

Identificadores químicos

CAS
3810-74-0
IUPAC Name
bis(N''-[(1R,2R,3S,4R,5R,6S)-3-[(diaminomethylidene)amino]-4-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy}-2,5,6-trihydroxycyclohexyl]guanidine); tris(sulfuric acid)
Molecular Formula
C42H84N14O36S3
InChI Key
QTENRWWVYAAPBI-YCRXJPFRSA-N
SMILES
OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]2N=C(N)N)O[C@@H](C)[C@]1(O)C=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]2N=C(N)N)O[C@@H](C)[C@]1(O)C=O
Comment
Colorimetric: ≥ 90.0%
Impurity content
Methanol (GC): ≤ 0.3%
Loss on Drying
≤ 7.0%
Assay (unspecified)
(Sulfate): 18.0 - 21.5%
Impurity content
Bacterial Endotoxins: ≤ 0.25 IU/mg

Descripción

Inhibits initiation and causes misreading of rRNA in protein synthesis Streptomycin sulfate is used to study the mechanisms of streptomycin resistance. It is used to inhibit bacterial contamination in cell culture applications in association with penicillin. It is an antibiotic drug initially used for tuberculosis treatment. It inhibits protein synthesis by binding to 30S ribosomal subunit, which induces the misreading of the genetic code. It is involved in the initiation of translation of DNA, thereby results in death for a susceptible bacterium. Further, it controls bacterial and fungal diseases of certain fruit, vegetables, seed, ornamental crops and algae in ornamental ponds and aquaria

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• Streptomycin sulfate is an aminoglycoside sulfate salt derived from Streptomyces griseus that shows antibacterial activity.
• It inhibits the initiation and causes misreading of rRNA in protein synthesis. This compound binds to the S12 protein of the bacterial 30S ribosomal subunit, thereby inhibiting peptide elongation and protein synthesis.
Application
• Streptomycin sulfate can be used to study the mechanisms of streptomycin resistance
• This compound can be used in laboratory applications combined with penicillin to inhibit bacterial contamination in in vitro cell culture
• Streptomycin sulfate shows antibiotic activity against Mycobacterium tuberculosis
• This compound can be used as a protein synthesis inhibitor
• It acts against gram-negative and gram-positive bacteria
• Streptomycin sulfate also shows a fungicide activity
• It can be used to remove nucleic acids from a biological extract
RUO – Research Use Only

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    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Acute oral toxicity
    Category 4
    Skin Sensitization
    Category 1
    Reproductive Toxicity
    Category 2
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H302 - Harmful if swallowed

    H317 - May cause an allergic skin reaction

    H361d - Suspected of damaging the unborn child

    Precautionary Statements

    P201 - Obtain special instructions before use

    P261 - Avoid breathing dust/fume/gas/mist/vapors/spray

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P301 + P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P308 + P313 - IF exposed or concerned: Get medical advice/attention