As a bifunctional reagent used in the synthesis of π -extended heteroarylfuran systems. Reactant involved in Suzuki coupling for synthesis of stable dye-sensitized solar cells. Reactant involved in synthesis of biologically active molecules including, heteroarylation for the synthesis of HIF-1 inhibitors, disalicylic acid-furanyl derivatives to inhibit ephrin binding, HIV-1 integrase inhibitors, epidermal growth factor receptor inhibitors.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Aplicaciones
Como reactivo bifuncional utilizado en la síntesis π de sistemas heteroarilfuranos extendidos. Reactivo implicado en el acoplamiento de Suzuki para la síntesis de células solares estables sensibles al tinte. Es un reactivo que se utiliza en la síntesis de moléculas biológicamente activas, que incluye la heteroarilación para la síntesis de inhibidores de HIF-1, los derivados de ácido disalicílico-furanilo para inhibir la unión de la efrina,los inhibidores de la integrasa del VIH-1, los inhibidores del receptor del factor de crecimiento epidérmico.
Solubilidad
Insoluble en agua.
Notas
Sensible al aire. Almacenar alejado del aire y de los agentes oxidantes. Mantener el recipiente bien cerrado en un lugar seco, fresco y bien ventilado. Almacenar en gas inerte.
RUO – Research Use Only
General References:
- S. Qu, et al. New diketo-pyrrolo-pyrrole (DPP) sensitizer containing a furan moiety for efficient and stable dye-sensitized solar cells.Dyes and Pigments.,2012,921384-1393.
- Se Hun Kim, et al. Effect of five-membered heteroaromatic linkers to the performance of phenothiazine-based dye-sensitized solar cells.Org. Lett.,2011,17(23), 6415-6424.
- Bifunctional reagent used in the synthesis of π -extended heteroarylfuran systems: Org. Biomol. Chem., 1, 1447 (2003).