This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• D(+)-Carvone belongs to terpene family and is considered a monoterpene ketone naturally found mainly in Achillea ageratum and Curcuma pierreana
Application
• D(+)-Carvone has shown a suppressant effect against high-fat diet induced weight gain in mice
• It has been used as a flavoring agent
• It has been used in organic synthesis as starting material for the asymmetric total synthesis of natural products, including the synthesis of the terpenoid quassin
• In vitro studies demonstrated that this compound can inhibit cellulase-induced capsidiol production in Nicotiana tabacum by interfering with protein isoprenylation
Literature References
Alsanea, S.; Liu, D. BITC and S-Carvone Restrain High-Fat Diet-Induced Obesity and Ameliorate Hepatic Steatosis and Insulin Resistance. Pharm Res. 2017, 34(11), 2241-2249.
Senthil Kumaran, R.; Mehta, G. A versatile, RCM based approach to eudesmane and dihydroagarofuran sesquiterpenoids from (-)-carvone: a formal synthesis of (-)-isocelorbicol. Tetrahedron. 2015, 71 (19), 1718-1731.
Huchelmann, A.; Gastaldo, C.; Veinante, M.; Zeng, Y.; Heintz, D.; Tritsch, D.; Schaller, H.; Rohmer, M.; Bach, T. J.; Hemmerlin, A. S-Carvone Suppresses Cellulase-Induced Capsidiol Production in Nicotiana tabacum by Interfering with Protein Isoprenylation. Plant Physiol. 2014, 164, 935-950.