Streptomycin sulfate

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Streptomycin sulfate

Streptomycin sulfate, CAS # 3810-74-0, is the sulfate salt form of streptomycin, and an aminoglycoside with antibacterial activity. It also shows a protein synthesis inhibitory activity.

Catalog Number	Quantity
455340250	25 g

Catalog number 455340250

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Price (EUR)

37,83

Online Exclusive

45,60

Save 7,77 (17%)

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Chemical Identifiers

CAS3810-74-0

IUPAC Namebis(N''-[(1R,2R,3S,4R,5R,6S)-3-[(diaminomethylidene)amino]-4-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy}-2,5,6-trihydroxycyclohexyl]guanidine); tris(sulfuric acid)

Molecular FormulaC42H84N14O36S3

InChI KeyQTENRWWVYAAPBI-YCRXJPFRSA-N

SMILESOS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]2N=C(N)N)O[C@@H](C)[C@]1(O)C=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]2N=C(N)N)O[C@@H](C)[C@]1(O)C=O

Specifications

Appearance (Color)White to off-white

Appearance (Form)Powder

Sulfate (SO4)18.0 to 21.5

Loss on drying=<7 %

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Streptomycin sulfate is an aminoglycoside sulfate salt derived from Streptomyces griseus that shows antibacterial activity.

• It inhibits initiation and causes misreading of rRNA in protein synthesis. This compound binds to the S12 protein of the bacterial 30S ribosomal subunit, thereby inhibiting peptide elongation and protein synthesis.

Application

• Streptomycin sulfate can be used to study the mechanisms of streptomycin resistance

• This compound can be used in laboratory applications combined with penicillin to inhibit bacterial contamination in in vitro cell culture

• Streptomycin sulfate shows antibiotic activity against Mycobacterium tuberculosis

• This compound can be used as a protein synthesis inhibitor

• It acts against gram-negative and gram-positive bacteria • Streptomycin sulfate also shows a fungicide activity

• It can be used to remove nucleic acids from a biological extract

RUO – Research Use Only

Literature References

Kou, Q. Y.; Li, J.; Zhao, B.; Wu, Z. L. Recovery of streptomycin sulfate from the wastewater using foam fractionation coupled with adsorption separation for reusing sodium dodecyl sulfate. J. Chem. Technol. Biotechnol. 2015, 90 (5), 874-879.

Evans, J. F.; Salvador, V.; George, S.; Trevino-Gutierrez, C.; Nunez, C. Mouse aorta-derived mesenchymal progenitor cells contribute to and enhance the immune response of macrophage cells under inflammatory conditions. Stem Cell Res. Ther. 2015, 6 (56), 1-15.

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Safety Data Sheets

Safety and Handling

Classification of the substance or mixture

CLP classification - Regulation(EC) No 1272/2008

Acute oral toxicity

Category 4

Skin Sensitization

Category 1

Reproductive Toxicity

Category 2

Label Elements

Signal Word

Warning

Hazard Statements

H302 - Harmful if swallowed

H317 - May cause an allergic skin reaction

H361d - Suspected of damaging the unborn child

Precautionary Statements

P201 - Obtain special instructions before use

P261 - Avoid breathing dust/fume/gas/mist/vapors/spray

P280 - Wear protective gloves/protective clothing/eye protection/face protection

P301 + P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell

P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

P308 + P313 - IF exposed or concerned: Get medical advice/attention