4-Methoxybenzeneboronic acid is used for Suzuki-Miyaura cross-coupling reactions, Pd-catalyzed direct arylation, Highly effective synthesis using palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water, Palladium-catalyzed stereoselective Heck-type reaction, Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence, Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides, Ruthenium catalyzed direct arylation, Rh-catalyzed asymmetric conjugate addition, Ligand-free copper-catalyzed coupling.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Methoxybenzeneboronic acid is used for Suzuki-Miyaura cross-coupling reactions, Pd-catalyzed direct arylation, Highly effective synthesis using palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water, Palladium-catalyzed stereoselective Heck-type reaction, Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence, Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides, Ruthenium catalyzed direct arylation, Rh-catalyzed asymmetric conjugate addition, Ligand-free copper-catalyzed coupling.
Solubility
Soluble in dimethyl sulfoxide and methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
RUO – Research Use Only
General References:
- S.A. Barker.; A.K. Chopra.; B.W. Hatt.; P.J. Somers. The interaction of areneboronic acids with monosaccharides . Carbohydrate Research. 1973, 26 (1), 33-40.
- S.A. Barker, B.W. Hatt, P.J. Somers. The effect of areneboronic acids on the alkaline conversion of d-glucose into d-fructose. Carbohydrate Research . 1973, 26 (1), 41-53.
- GC reagent for diols: J. Chromat., 158, 33 (1978), 186, 307 (1979).
- For an illustrative example of the silver oxide promoted Suzuki coupling with sensitive ɑ-halo enones, under extremely mild conditions, see: Org. Synth., 75, 69 (1997):