Thermo Scientific Chemicals

Glyoxylic acid monohydrate, 97%, Thermo Scientific Chemicals

Catalog number: A16058.22
100 g, Each
Thermo Scientific Chemicals

Glyoxylic acid monohydrate, 97%, Thermo Scientific Chemicals

Catalog number: A16058.22
100 g, Each
Quantity
Catalog number: A16058.22
also known as A16058-22
Price (EUR)
Quantity
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Chemical Identifiers

CAS
563-96-2
IUPAC Name
2,2-dihydroxyacetate
Molecular Formula
C2H3O4
InChI Key
GOCCREQJUBABAL-UHFFFAOYSA-M
SMILES
OC(O)C([O-])=O
Form
Crystals or powder or crystalline powder or lumps or fused solid
Assay (Aqueous acid-base Titration)
≥96.0 to ≤104.0%
Appearance (Color)
White to pale cream to pale yellow
Water Content (Karl Fischer Titration)
10.85-26.74% (0.5-1.5 waters)
Identification (FTIR)
Conforms

Description

Glyoxylic acid is a reagent for sulfinylmaleate synthesis. It is one of the chemicals used in the Hopkins Cole reaction. It is involved to check the presence of tryptophan in proteins. It is condensed with urea and 1,2-diaminobenzene to form heterocycles. It also undergoes Friedel-Crafts and cyclocondensation reactions to form bis(pentamethylphenyl) acetic acid and a beta-carboline respectively. It is employed in the synthesis of a sulfinylmaleate, which serves as an efficient dienophile for enantioselective Diels-Alder cycloadditions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Glyoxylic acid is a reagent for sulfinylmaleate synthesis. It is one of the chemicals used in the Hopkins Cole reaction. It is involved to check the presence of tryptophan in proteins. It is condensed with urea and 1,2-diaminobenzene to form heterocycles. It also undergoes Friedel-Crafts and cyclocondensation reactions to form bis(pentamethylphenyl) acetic acid and a beta-carboline respectively. It is employed in the synthesis of a sulfinylmaleate, which serves as an efficient dienophile for enantioselective Diels-Alder cycloadditions.

Solubility
Soluble in water, dimethyl sulfoxide and alcohol. Insoluble in diethyl ether and hydrocarbons.

Notes
Hygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible withbases, oxidizing agents and reducing agents.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Corrosion/Irritation
    Category 1
    Serious Eye Damage/Eye Irritation
    Category 1
    Skin Sensitization
    Category 1
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H314 - Causes severe skin burns and eye damage

    H317 - May cause an allergic skin reaction

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting

    P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P310 - Immediately call a POISON CENTER or doctor/physician