Thermo Scientific Chemicals

Methyl Trifluoroacetate, 98+%, Thermo Scientific Chemicals

Catalog number: A17338.30
250 g, Each
Thermo Scientific Chemicals

Methyl Trifluoroacetate, 98+%, Thermo Scientific Chemicals

Catalog number: A17338.30
250 g, Each
Quantity
Catalog number: A17338.30
also known as A17338-30
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
431-47-0
Form
Liquid
Assay (GC)
>98.0%
Refractive Index
<1.3000 @ 20?C
Appearance (Color)
Clear, colorless

Description

Useful reagent for trifluoroacetylation of amines under mild conditions. In the presence of 1,1,3,3-Tetramethyl­guanidine, has also been used for the N-acylation of amino acids. It is used as an intermediate in the synthesis of pharmaceutical and agricultural chemicals. The chemical reactions usually involve nucleophilic substitution of the ester and are useful for the preparation of trifluoroacylated compounds.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Useful reagent for trifluoroacetylation of amines under mild conditions. In the presence of 1,1,3,3-Tetramethyl­guanidine, has also been used for the N-acylation of amino acids. It is used as an intermediate in the synthesis of pharmaceutical and agricultural chemicals. The chemical reactions usually involve nucleophilic substitution of the ester and are useful for the preparation of trifluoroacylated compounds.

Solubility
Not miscible or difficult to mix in water.

Notes
Moisture sensitive. Store away from strong bases, water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect from humidity.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Flammable liquids
    Category 2
    Skin Corrosion/Irritation
    Category 1
    Serious Eye Damage/Eye Irritation
    Category 1
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H314 - Causes severe skin burns and eye damage

    Physical Hazards

    H225 - Highly flammable liquid and vapor

    Precautionary Statements

    P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking

    P240 - Ground and bond container and receiving equipment

    P280 - Wear eye protection/ face protection

    P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P310 - Immediately call a POISON CENTER or doctor/physician