2-(Phenoxymethyl)oxirane is used in the synthesis of hydrazide-containing inhibitors of HIV-1 integrase.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-(Phenoxymethyl)oxirane is used in the synthesis of hydrazide-containing inhibitors of HIV-1 integrase.
Solubility
Soluble in water (2.4g/L).
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- Zhao, H. et al. Hydrazide-Containing Inhibitors of HIV-1 Integrase.J. Med. Chem.199740(6), 937-941.
- E Van den Eeckhout; A De Bruyn; H Pepermans; E L Esmans; I Vryens, J Claereboudt; M Claeys; J E Sinsheimer. Adduct formation identification between phenyl glycidyl ether and 2'-deoxyadenosine and thymidine by chromatography, mass spectrometry and nuclear magnetic resonance spectroscopy.Journal of Chromatography A.1991541(1-2), 317-331.