Thermo Scientific Chemicals

Thiophene-2-boronic acid, 97%, Thermo Scientific Chemicals

Catalog number: B23071.14
25 g, Each
Thermo Scientific Chemicals

Thiophene-2-boronic acid, 97%, Thermo Scientific Chemicals

Catalog number: B23071.14
25 g, Each
Quantity
Catalog number: B23071.14
also known as B23071-14
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
6165-68-0
IUPAC Name
(thiophen-2-yl)boronic acid
Molecular Formula
C4H5BO2S
InChI Key
ARYHTUPFQTUBBG-UHFFFAOYSA-N
SMILES
OB(O)C1=CC=CS1
Appearance (Color)
White to cream
Form
Powder
Assay (Aqueous acid-base Titration)
≥96.0 to ≤104.0%
Identification (FTIR)
Conforms

Description

Thiophene-2-boronic acid is a reagent used for Palladium-catalyzed Suzuki-Miyaura cross-couplings, Copper-catalyzed nitration reactions, Chain-growth catalyst transfer polycondensation of conjugated alternating copolymer, Ferric perchlorate-promoted reaction of fullerene to give fullerenyl boronic esters. It is also used in the preparation of Amino pyridine-based inhibitors of mitotic kinase Nek2 with potential antipoliferative effects in cancer tumors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiophene-2-boronic acid is a reagent used for Palladium-catalyzed Suzuki-Miyaura cross-couplings, Copper-catalyzed nitration reactions, Chain-growth catalyst transfer polycondensation of conjugated alternating copolymer, Ferric perchlorate-promoted reaction of fullerene to give fullerenyl boronic esters. It is also used in the preparation of Amino pyridine-based inhibitors of mitotic kinase Nek2 with potential antipoliferative effects in cancer tumors.

Solubility
Soluble in methanol.

Notes
Store in a cool, dry conditions, in well sealed conditions. Store away from oxidizing agents.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Specific target organ toxicity - (single exposure)
    Category 3
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H315 - Causes skin irritation

    H319 - Causes serious eye irritation

    H335 - May cause respiratory irritation

    Precautionary Statements

    P261 - Avoid breathing dust/fume/gas/mist/vapors/spray

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing