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Proteintech
WDR35 Polyclonal Antibody
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Application
Product Details
26701-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Unconjugated
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: AECYYMLEDY EGLENLAISL PENHKLLPEI AQMFVRVGMC EQAVTTFLKC SQPKAAVDTC VHLNQWNKAV ELAKNHSMKE IGSLLARYAS HLLEKNKTLD AIELYRKANY FFDAAKLMFK IADEEAKKGS KPLRVKKLYV LSALLIEQYH EQMKNAQRGK VKGKSSEATS ALAGLLEEEV LSTTDRFTDN AWRGAEAYHF FILAQRQLYE GCVDTALKTA LHLKDYEDII PPVEIYSLLA LCACAGRAFG TCSKAFIKLK SLETLSSEQK QQYEDLALEI FTKHTSKDNR KPELDSLMEG GEGKLPTCVA TGSPITEYQF WMCSVCKHGV LAQEISHYSF CPLCHSPVG
Target Information
WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Intraflagellar transport protein 121 homolog; naofen; WD repeat-containing protein 35
Gene Aliases: CED2; IFT121; IFTA1; KIAA1336; SRTD7; WDR35
UniProt ID: (Human) Q9P2L0
Entrez Gene ID: (Human) 57539, (Dog) 475677
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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