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Tolbutamide, 98%, Thermo Scientific Chemicals
Référence: B21698.30
250 g, Each
Thermo Scientific Chemicals
Tolbutamide, 98%, Thermo Scientific Chemicals
Référence: B21698.30
250 g, Each
Quantité
Référence: B21698.30
également connu sous le numéro B21698-30
Prix (EUR)
481,50 Prix en ligne
535,00
Each
Quantité
-
Identifiants chimiques
CAS
64-77-7
IUPAC Name
3-butyl-1-(4-methylbenzenesulfonyl)urea
Molecular Formula
C12H18N2O3S
InChI Key
JLRGJRBPOGGCBT-UHFFFAOYSA-N
SMILES
CCCCNC(=O)NS(=O)(=O)C1=CC=C(C)C=C1
Spécifications
Fiche de spécificationsAssay (Aqueous acid-base Titration)
≥97.5 to ≤102.5% (UK-sourced material)
Assay (HPLC)
≥97.5%
Comment
Material sourced in UK and US
Assay from Supplier's CofA
≥97.5% (US-sourced material)
Melting Point (clear melt)
126-130°C
Description
Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.
Solubility
Soluble in chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.
Solubility
Soluble in chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
RUO – Research Use Only
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Sécurité et manipulation
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Skin Sensitization
Category 1
Label Elements
Signal Word
Warning
Hazard Statements
H302 - Harmful if swallowed
H317 - May cause an allergic skin reaction
Precautionary Statements
P280 - Wear protective gloves/protective clothing
P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P312 - Call a POISON CENTER or doctor if you feel unwell
P333 + P313 - If skin irritation or rash occurs: Get medical advice/attention