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            • Primary Antibodies ›
            • OBFC1 Antibodies

            Invitrogen

            OBFC1 Polyclonal Antibody

            View all (8) OBFC1 antibodies
            Datasheet
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            Catalog # PA5-111089
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            Price (HKD)
            4,564.00
            100 µL
             
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            Cite OBFC1 Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            OBFC1 Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            OBFC1 Antibody (PA5-111089) in ICC/IF

            Immunofluorescent analysis of OBFC1 in human cell line U-251 MG using OBFC1 Polyclonal Antibody (Product # PA5-111089). Staining shows localization to nucleus and nucleoli fibrillar center.
            View Product

            OBFC1 Antibody in Immunocytochemistry (ICC/IF)

            Product Details

            PA5-111089

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            0.04-0.4 µg/mL
            -

            Immunocytochemistry (ICC/IF)

            0.25-2 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant Protein corresonding to Human OBFC1. Recombinant protein control fragment (Product #RP-97057).
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.08 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.2, with 40% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2856499

            Product Specific Information

            Immunogen sequence: DTIRVRGSIR TYREEREIHA TTYYKVDDPV WNIQIARMLE LPTIYRKVYD QPFHSSALEK EEALSNPGAL DLPSLTSLLS EKAKEFLMEN RVQSF

            Target Information

            OBFC1 is a component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: alpha accessory factor 44; CST complex subunit STN1; oligonucleotide/oligosaccharide-binding fold containing 1; Oligonucleotide/oligosaccharide-binding fold-containing protein 1; replication protein A 32 kDa subunit; Suppressor of cdc thirteen homolog

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            Gene Aliases: AAF-44; AAF44; bA541N10.2; OBFC1; RPA-32; STN1

            View more View less

            UniProt ID: (Human) Q9H668

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            Entrez Gene ID: (Human) 79991

            View more View less

            Function(s)

            single-stranded DNA binding protein binding telomerase inhibitor activity telomeric DNA binding single-stranded telomeric DNA binding

            Process(es)

            telomere maintenance telomere maintenance via telomere lengthening telomere capping positive regulation of telomere maintenance via telomerase positive regulation of DNA replication positive regulation of telomerase activity negative regulation of telomerase activity regulation of telomere maintenance via telomere lengthening
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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