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Description | IMAGEN™ Chlamydia Kit |
Detectable Analytes | Chlamydia antigen |
Type | Chlamydia Testing Kit |
For Use With (Application) | Enzyme Immunoassay Detection |
Includes | 2 x positive control slide, mounting fluid, Chlamydia test reagent, instructions for use |
Quantity | 50 Tests |
Shelf Life | 24 Months |
Unit Size | Each |
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Chlamydia trachomatis has been recognized as a frequent cause of sexually transmitted diseases1,2 and has been shown to cause a variety of human infections, some of which may be asymptomatic.
Use IMAGEN Chlamydia Direct Kit as a rapid, sensitive and specific method for direct detection and identification of Chlamydiae in clinical specimens or cell cultures.
Chlamydiae are obligate intracellular parasites closely related to Gram-negative bacteria1. The genus Chlamydia contains three known species, Chlamydia trachomatis, Chlamydia psittaci and Chlamydia pneumoniae. The life cycle of Chlamydiae is complex but two main structures are recognized, the infectious elementary body and the reticulate body.
Currently, there are three main diagnostic methods used for the detection of Chlamydia in clinical specimens. Firstly, by isolation of the organism and visualization—viable elementary bodies present in clinical specimens infect tissue culture cells and the resultant inclusions are detected by staining techniques, e.g., iodine or immunofluorescence. Secondly, by direct demonstration of Chlamydia in clinical specimens using a fluorescein-labeled monoclonal antibody. Thirdly, by enzyme immunoassay (e.g., IDEIA™ PCE Chlamydia Kit) to determine the presence of Chlamydia antigen in clinical specimens3.
Direct immunofluorescence techniques utilising fluorescein-labeled monoclonal antibodies4,5,6 have been shown to have good correlation when compared to cell culture techniques for the detection of C. trachomatis.
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1. Chlamydial Disease (1983) Ed. Darougar S British Medical Bulletin 39: 107-203.