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An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.
For use in combination with the Fluorescein-IKK peptide substrate (PV3507) to evaluate inhibitors in medium to high throughput screening applications.
For use in combination with the Fluorescein-IKK peptide substrate (PV3507) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
規格
Conjugate
Tb (Terbium)/FITC
Gene ID (Entrez)
1147, 2869, 3551
Assay Entry
Biochemical terbium phospho-specific activity
Format
384-well Plate
Excitation/Emission
340⁄490, 520
Reactivity
Human
Shipping Condition
Dry Ice
Readout
End Point
Reactivity abrv
Hu
Target Entry
IKBKE, CHUK, GRK5, GRK6, TBK1, IKBKB
Target Enzyme
Serine⁄Threonine Kinases
Technique
TR-FRET
Validated Kinases
CHUK, GRK5, GRK6, IKBKB, IKBKE
Product Line
LanthaScreen™
內容物與存放
Terbium-labeled anti-IkappaBalpha [pSer32] antibody in HEPES buffered saline. Store at -20°C.
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