Thermo Scientific Pierce AMAS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of aRead more
Thermo Scientific Pierce AMAS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a very short spacer arm (4.4 angstroms).
Features of AMAS:
• Reactive groups: NHS ester and maleimide • Reactive towards: amino and sulfhydryl groups • Shortest of aliphatic spacer series which includes AMAS, BMPS, GMBS and EMCS • NHS ester end couples with primary amines at pH 7-9, forming stable amide bonds • Maleimide reacts with -SH groups at pH 6.5-7.5, forming stable thioether linkages • Non-cleavable • Water-insoluble (dissolve first in DMF or DMSO) • Very short aliphatic spacer has low potential for eliciting an immune response
For Research Use Only. Not for use in diagnostic procedures.