Hypersil™ PREP HS C8 HPLC Columns

Name: Hypersil™ PREP HS C8 HPLC Columns
SKU: 41103-052130

Use these preparative columns for scale-up purification with high phase loading. They are suitable for all USP-L7 applications.

Technical SupportCustomer Service

Change view

Catalog Number	Length (Metric)	Diameter (Metric)	Particle Size	Column Format
41103-052130	50 mm	2 mm	3 μm	Preparative Column, Standard
41103-054630	50 mm	4.6 mm	3 μm	Preparative Column, Standard
41103-102130	100 mm	2 mm	3 μm	Preparative Column, Standard
41103-104630	100 mm	4.6 mm	3 μm	Preparative Column, Standard
41103-152130	150 mm	2 mm	3 μm	Preparative Column, Standard
41103-154630	150 mm	4.6 mm	3 μm	Preparative Column, Standard
41103-252130	250 mm	2 mm	3 μm	Preparative Column, Standard
41103-254630	250 mm	4.6 mm	3 μm	Preparative Column, Standard
41105-052130	50 mm	2 mm	5 μm	Preparative Column, Standard
41105-054630	50 mm	4.6 mm	5 μm	Preparative Column, Standard
41105-059070A	50 mm	10 mm	5 μm	Preparative Column, Standard
41105-059270A	50 mm	20 mm	5 μm	Preparative Column, Standard
41105-059270XL	50 mm	25 mm	5 μm	Preparative Column, Xtended Life
41105-102130	100 mm	2 mm	5 μm	Preparative Column, Standard
41105-104630	100 mm	4.6 mm	5 μm	Preparative Column, Standard
41105-109070A	100 mm	10 mm	5 μm	Preparative Column, Standard
41105-109270A	100 mm	20 mm	5 μm	Preparative Column, Standard
41105-109270XL	100 mm	25 mm	5 μm	Preparative Column, Xtended Life
41105-152130	150 mm	2 mm	5 μm	Preparative Column, Standard
41105-154630	150 mm	4.6 mm	5 μm	Preparative Column, Standard
41105-159070A	150 mm	10 mm	5 μm	Preparative Column, Standard
41105-159270A	150 mm	20 mm	5 μm	Preparative Column, Standard
41105-159270XL	150 mm	25 mm	5 μm	Preparative Column, Xtended Life
41105-159370A	150 mm	30 mm	5 μm	Preparative Column, Standard
41105-159370XL	150 mm	30 mm	5 μm	Preparative Column, Xtended Life
41105-159570A	150 mm	50 mm	5 μm	Preparative Column, Standard
41105-159570XL	150 mm	50 mm	5 μm	Preparative Column, Xtended Life
41105-252130	250 mm	2 mm	5 μm	Preparative Column, Standard
41105-254630	250 mm	4.6 mm	5 μm	Preparative Column, Standard
41105-259070A	250 mm	10 mm	5 μm	Preparative Column, Standard
41105-259270A	250 mm	20 mm	5 μm	Preparative Column, Standard
41105-259270XL	250 mm	25 mm	5 μm	Preparative Column, Xtended Life
41105-259370A	250 mm	30 mm	5 μm	Preparative Column, Standard
41105-259370XL	250 mm	30 mm	5 μm	Preparative Column, Xtended Life
41105-259570A	250 mm	50 mm	5 μm	Preparative Column, Standard
41105-259570XL	250 mm	50 mm	5 μm	Preparative Column, Xtended Life
41110-018823A	8 mm	10 mm	10 μm	Guard Column
41110-019023A	20 mm	10 mm	10 μm	Guard Column
41110-019323A	30 mm	10 mm	10 μm	Guard 1/16 in.
41110-019323B	30 mm	10 mm	10 μm	Guard 1/8 in.
41110-029323A	30 mm	20 mm	10 μm	Guard 1/16 in.
41110-029323B	30 mm	20 mm	10 μm	Guard 1/8 in.
41110-059070A	50 mm	10 mm	10 μm	Preparative Column, Standard
41110-059270A	50 mm	20 mm	10 μm	Preparative Column, Standard
41110-059270XL	50 mm	25 mm	10 μm	Preparative Column, Xtended Life
41110-109070A	100 mm	10 mm	10 μm	Preparative Column, Standard
41110-109270A	100 mm	20 mm	10 μm	Preparative Column, Standard
41110-109270XL	100 mm	25 mm	10 μm	Preparative Column, Xtended Life
41110-159070A	150 mm	10 mm	10 μm	Preparative Column, Standard
41110-159270A	150 mm	20 mm	10 μm	Preparative Column, Standard
41110-159270XL	150 mm	25 mm	10 μm	Preparative Column, Xtended Life
41110-159370A	150 mm	30 mm	10 μm	Preparative Column, Standard
41110-159370XL	150 mm	30 mm	10 μm	Preparative Column, Xtended Life
41110-159570A	150 mm	50 mm	10 μm	Preparative Column, Standard
41110-159570XL	150 mm	50 mm	10 μm	Preparative Column, Xtended Life
41110-259070A	250 mm	10 mm	10 μm	Preparative Column, Standard
41110-259270A	250 mm	20 mm	10 μm	Preparative Column, Standard
41110-259270XL	250 mm	25 mm	10 μm	Preparative Column, Xtended Life
41110-259370A	250 mm	30 mm	10 μm	Preparative Column, Standard
41110-259370XL	250 mm	30 mm	10 μm	Preparative Column, Xtended Life
41110-259570A	250 mm	50 mm	10 μm	Preparative Column, Standard
41110-259570XL	250 mm	50 mm	10 μm	Preparative Column, Xtended Life

62 Options

Catalog number 41103-052130

Price (JPY)/ Each

Request A Quote

Length (Metric):

50 mm

Diameter (Metric):

2 mm

Particle Size:

3 μm

Column Format:

Preparative Column, Standard

Get maximum loading for your scale up from analytical to a prep LC method with Thermo Scientific™ Hypersil™ PREP HS C8 reversed phase preparative HPLC column. With similar selectivity to C18 columns and predictable elution order, C8 columns are ideal for analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations. By providing high surface area particles with a 100Å pore size, and a variety of dimensions including an option for XtendedLife hardware, which improves column lifetime by maintaining a uniform packed bed.

Similar selectivity, less retention than C18 columns

Successful retention and separation of moderately hydrophobic analytes.
Ideal for fatty acids, which are too hydrophobic for analysis using C18 columns.
C8 (USP L7) selectivity - high surface area particle with 100Å pore size.
pH stable from 2 to 8.
Maximum temperature of 60°C.

Faster separations

Higher analytical throughput compared to C18 alkyl chain chemistry.
Quicker compound elution due to reduced hydrophobic interactions.

Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.

Standard Threaded and Standard Flange Hardware

Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
Standard threaded hardware for column i.d. < 40mm.
Standard flange hardware for column i.d. ≥ 40mm.
Standard hardware can be modified on request to be compatible with SFC.

XtendedLife Hardware

Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
Compatible with SFC and is available in dimensions up to 50mm i.d.

Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.

Customer Specific Orders

If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
Please contact your local sales representative for Customer Specific Orders.
Custom built columns are not eligible for returns.

Specifications

Column FormatPreparative Column, Standard

Diameter (Metric)2 mm

Length (Metric)50 mm

Max. Pressure5800 psi (400 bar)

Particle Size3 μm

pH2 to 8

Pore Size100 Å

Surface Area350 m²/g

Temperature60°C

USP TypeL7

Stationary PhaseC8

Packing MaterialSpherical, Fully Porous, Ultrapure Silica

Carbon Load7%

Column TypeReversed Phase

EndcappedYes

PhaseReversed Phase

Unit SizeEach