Flurbiprofen, 98%

Name: Flurbiprofen, 98%
SKU: 454660050

Flurbiprofen, CAS # 5104-49-4, is a monocarboxylic acid-based nonsteroidal anti-inflammatory (NSAID).

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Catalog number 454660050

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Chemical Identifiers

CAS5104-49-4

IUPAC Name2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid

Molecular FormulaC15H13FO2

InChI KeySYTBZMRGLBWNTM-UHFFFAOYNA-N

SMILESCC(C(O)=O)C1=CC=C(C(F)=C1)C1=CC=CC=C1

Specifications

Specification Sheet

Infrared spectrumConforms

HPLC>=97.5 %

Appearance (Form)Powder

Melting point110°C to 116°C

Appearance (Color)White to off-white

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Flurbiprofen is composed of a 2-fluoro-[1,1'-biphenyl-4-yl] moiety attached to propionic acid

• Flurbiprofen works by inhibiting prostaglandin-endoperoxide synthase and reducing the production of prostaglandins and pyrogens

Applications

• Flurbiprofen is useful for studying pathways associated with prostaglandin production

• It is suitable for laboratory research on pain, inflammation, ocular pressure, and postoperative recovery

RUO – Research Use Only

Literature References

Sun, M.; Cong, X.; Chang, E.; Miao, M.; Zhang, J. Efficacy of Flurbiprofen for Postoperative Pain in Chinese Surgical Patients: A Meta-Analysis. J Surg Res. 2020, 252:80-88.

Caban-Toktas, S.; Sahin, A.; Lule, S.; Esendagli, G.; Vural, I.; Karlı Oguz, K.; Soylemezoglu, F.; Mut, M.; Dalkara, T.; Khan, M.; Capan, Y. Combination of Paclitaxel and R-flurbiprofen loaded PLGA nanoparticles suppresses glioblastoma growth on systemic administration. Int J Pharm. 2020, 578,119076.