Indole-3-carboxylic acid is used as a raw material in synthesis. The structures of the derivatives of indole-3-carboxylic acid were studied using gas chromatography with high resolution mass spectrometry (GC-HRMS), ultra-high performance liquid chromatography in combination with high resolution tandem mass spectrometry (UHPLC-HRMS), nuclear magnetic resonance spectroscopy (NMR) and Fourier transform infrared spectroscopy. Reactant for preparation of: Anticancer agents, Derivatives of amino acids and peptides, Serotonin 5-HT4 receptor antagonists, Primary acylureas, Inhibitors of Gli1-mediated transcription in the Hedgehog pathway, Serotonin 5-HT6 antagonists, Very Late Antigen-4 (VLA-4) sntagonists, EphB3 receptor tyrosine kinase inhibitors, Potential Therapeutic Agent for Alzheimer?s Disease, Vinyl ester pseudotripeptide proteasome inhibitors
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Indole-3-carboxylic acid is used as a raw material in synthesis. The structures of the derivatives of indole-3-carboxylic acid were studied using gas chromatography with high resolution mass spectrometry (GC-HRMS), ultra-high performance liquid chromatography in combination with high resolution tandem mass spectrometry (UHPLC-HRMS), nuclear magnetic resonance spectroscopy (NMR) and Fourier transform infrared spectroscopy. Reactant for preparation of: Anticancer agents, Derivatives of amino acids and peptides, Serotonin 5-HT4 receptor antagonists, Primary acylureas, Inhibitors of Gli1-mediated transcription in the Hedgehog pathway, Serotonin 5-HT6 antagonists, Very Late Antigen-4 (VLA-4) sntagonists, EphB3 receptor tyrosine kinase inhibitors, Potential Therapeutic Agent for Alzheimer′s Disease, Vinyl ester pseudotripeptide proteasome inhibitors
Solubility
Soluble in 95% Ethanol: 50 mg/ml, also soluble in methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents. Stable under ordinary conditions.
RUO – Research Use Only
General References:
- G Smith.; UD Wermuth.; PC Healy. Indole-3-carboxylic acid. Acta Crystallographica Section E. 2003, E59, (1), 1776-1777.
- G Quartarone.; M Battilana.; L Bonaldo.; T Tortato. Investigation of the inhibition effect of indole-3-carboxylic acid on the copper corrosion in 0.5 MH 2 SO 4. Corrosion Science. 2008, 50, (12), 3467-3474.