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4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%, Thermo Scientific Chemicals
Catalog number: H26473.03
1 g, Each
Thermo Scientific Chemicals
4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%, Thermo Scientific Chemicals
Catalog number: H26473.03
1 g, Each
Quantity
Catalog number: H26473.03
also known as H26473-03
Price (JPY)
Chemical Identifiers
CAS
30827-99-7
IUPAC Name
hydrogen 4-(2-aminoethyl)benzene-1-sulfonyl fluoride chloride
Molecular Formula
C8H11ClFNO2S
InChI Key
WRDABNWSWOHGMS-UHFFFAOYSA-N
SMILES
[H+].[Cl-].NCCC1=CC=C(C=C1)S(F)(=O)=O
Specifications
Specification SheetForm
Powder
Melting Point
ca. 180-190?C dec.
Appearance (Color)
White
Proton NMR
To conform to structure
Assay (HPLC)
≥96.0%
Description
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.
Solubility
Soluble in water 50 mg/mL or 100% ethanol.
Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air, moisture.
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.
Solubility
Soluble in water 50 mg/mL or 100% ethanol.
Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air, moisture.
RUO – Research Use Only
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