Thermo Scientific Chemicals

Methylene Blue trihydrate, Thermo Scientific Chemicals

Catalog number: J60823.30
250 g, Each
Thermo Scientific Chemicals

Methylene Blue trihydrate, Thermo Scientific Chemicals

Catalog number: J60823.30
250 g, Each
Quantity
Catalog number: J60823.30
also known as J60823-30
Price (JPY)

Chemical Identifiers

CAS
7220-79-3
IUPAC Name
3,7-bis(dimethylamino)-5λ⁴-phenothiazin-5-ylium trihydrate chloride
Molecular Formula
C16H24ClN3O3S
InChI Key
XQAXGZLFSSPBMK-UHFFFAOYSA-M
SMILES
O.O.O.[Cl-].CN(C)C1=CC2=[S+]C3=CC(=CC=C3N=C2C=C1)N(C)C
Loss on Drying
8.0 to 18.0%
Assay (unspecified)
0.02% Zinc max.
Assay (unspecified)
98-103%
Assay (unspecified)
0.02% Copper max.
Residue on ignition
1.2% max.

Description

Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.

Solubility
Soluble in water, alcohol and chloroform. Insoluble in ether.

Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only

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