Isoproterenol hydrochloride is used as a selective β-adrenergic agonist, increases cytosolic cAMP.
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Applications
Isoproterenol hydrochloride is used as a selective β-adrenergic agonist, increases cytosolic cAMP.
Solubility
Soluble in water (50 mg/ml at 25°C), ethanol (20 mg/ml), methanol, DMSO (50 mg/ml at 25°C), and phosphate buffered saline (50 mM).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
RUO – Research Use Only
Lotti et al. Characterization of the adrenoreceptor activities of isoprenaline in the field stimulated rat vas deferens: selective supersensitivity to beta 2-mediated responses following reserpine treatment.. J.Auton.Pharmacol. 1982, 2, (3), 169-74.
Schmitt and Stork. β2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein Rap1 and the serine/threonine kinase B-Raf. J.Biol.Chem. 2000, 275, (33), 25342-50.