Thermo Scientific Chemicals

3,4-Dichloroisocoumarin, 98%, Thermo Scientific Chemicals

Catalog number: J65198.MA
10 mg, Each
Thermo Scientific Chemicals

3,4-Dichloroisocoumarin, 98%, Thermo Scientific Chemicals

Catalog number: J65198.MA
10 mg, Each
Quantity
Catalog number: J65198.MA
also known as J65198-MA
Price (JPY)

Chemical Identifiers

CAS
51050-59-0
IUPAC Name
3,4-dichloro-1H-isochromen-1-one
Molecular Formula
C9H4Cl2O2
InChI Key
SUGXUUGGLDCZKB-UHFFFAOYSA-N
SMILES
ClC1=C(Cl)C2=CC=CC=C2C(=O)O1
Assay (unspecified)
>98.5%

Description

Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It is an inhibitor of Chymotrypsin and Trypsin. ,4 Dichloroisocoumarin also inhibits granzymes A, B, and H, cathepsin G, neutrophil elastase, proteinase and blocks apoptotic internucleosomal DNA cleavage in thymocytes without the involvement of endonucleases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It is an inhibitor of Chymot
RUO – Research Use Only

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