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GeneBLAzer™ GPR10 CRE-bla CHO-K1 cells contain the human Prolactin Releasing Peptide (GPR10) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat. No. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.
The GeneBLAzer™ GPR10 CRE-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of PrRP20. In addition, GeneBLAzer™ GPR10 CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
The GPR10 receptor has been implicated in a variety of metabolic disorders, including lactation, the regulation of food intake, and other physiological functions.
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