Pierce™ Premium Grade EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)
Pierce™ Premium Grade EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)
Thermo Scientific™

Pierce™ Premium Grade EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)

Thermo Scientific Pierce Premium Grade EDC is our highest quality formulation of this popular carbodiimide crosslinker, specially characterized for applicationsRead more
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Catalog NumberQuantity
PG820791 g
PG8207325 g
Catalog number PG82079
Price (KRW)
148,000
Online offer
Ends: 30-Sep-2025
173,000
Save 25,000 (14%)
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Quantity:
1 g
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Price (KRW)
148,000
Online offer
Ends: 30-Sep-2025
173,000
Save 25,000 (14%)
Each
Add to cart
Thermo Scientific Pierce Premium Grade EDC is our highest quality formulation of this popular carbodiimide crosslinker, specially characterized for applications where product integrity and risk minimization are paramount.

Features of Premium Grade EDC:

EDC—carbodiimide crosslinker for conjugation between carboxylates and amines
High quality—identity and purity confirmed by several tests
Product integrity—enhanced level of testing and characterization compared to standard grade
Lot retention—ample supply of past lots retained to ensure future process testing
Change management—Change Control Notification (CCN) service
Consistent manufacture—batch-specific manufacturing documentation review

Compared to the standard grade product, Premium Grade EDC provides more clearly defined quality and product support by including (a) increased analytical testing and product characterization, (b) greater batch-specific information and quality assurance review, (c) extensive lot sample retention and (d) change control notification. EDC is 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride, a water-soluble carbodiimide crosslinker that activates carboxyl groups for spontaneous reaction with primary amines, enabling peptide immobilization and hapten-carrier protein conjugation. In the presence of N-hydroxysulfosuccinimide (sulfo-NHS), EDC can be used to convert carboxyl groups to amine-reactive sulfo-NHS esters. This is accomplished by mixing the EDC with a carboxyl containing molecule and adding sulfo-NHS.

Specifications of Premium Grade EDC
We manufacture crosslinking reagents to ensure the highest possible overall product integrity, consistency and performance for the intended research applications.
• Visual: White crystalline powder, free of foreign matter
• Identity: IR scan shows only peaks characteristic of EDC
• Water content: Karl Fischer titration, ≤ 2%
• Trace metals: All metals, including lead, ≤ 50 ppm

Applications:
• Conjugate carboxyl and amino groups among peptides and proteins
• Couple haptens to immunogenic carrier proteins (e.g., attach a peptide to KLH)
Immobilize peptide antigens to affinity-purify antibodies
• Create NHS-activated, amine-reactive labeling compounds
• Crosslink proteins to carboxyl coated beads or surfaces
• Activate nanoparticles with amine-reactive sulfo-NHS esters

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)
Pierce™ Premium Grade Sulfo-NHS (N-hydroxysulfosuccinimide)
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Cell PermeabilityNo
FormSolid
Labeling MethodChemical Labeling
Molecular Weight (g/mol)191.7
PEGylatedNo
Product LinePierce™
Quantity1 g
Reactive MoietyCarbodiimide
Shipping ConditionRoom Temperature
SolubilityWater
Spacer Arm Length0.0 Å
Water SolubleYes
Chemical ReactivityAmine-Carboxyl
CleavableNo
Crosslinker TypeHeterobifunctional
FormatStandard, Single-use, Premium-grade
Product TypeCrosslinker
SpacerShort (<10 Å)
Unit SizeEach
Contents & Storage
Upon receipt store desiccated at -20°C.

Frequently asked questions (FAQs)

Is your EDAC compound the same as your EDC compound?

Yes, both acronyms are used for the same compound. The chemical name for EDC is 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide and the chemical name for EDAC is N-3-(3-dimethylaminopropyl)-N-ethyl-carbodiimide. Both of these compounds are structurally equivalent.

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