The red-fluorescent Alexa Fluor® 594 alkyne can be reacted with azides via a copper-catalyzed click reaction. Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moities to label and detect a molecule of interest using a two-step procedure. The two-step reaction procedure involves a copper-catalyzed triazole formation of an azide and an alkyne. Click reactions have several characteristics: the reaction between the detection moieties is efficient; no extreme temperatures or solvents are required; the reaction product is stable; the components of the reaction are bioinert; and perhaps most importantly, no side reactions occur – the label and detection tags react selectively and specifically with one another. Unlike traditional chemical reactions utilizing succinimidyl esters or maleimides that target amines and sulfhydryls – functional groups that are not unique – click chemistry-labeled molecules can be applied to complex biological samples and be detected with unprecedented sensitivity due to extremely low background.
For Research Use Only. Not for use in diagnostic procedures.
사양
형식
Solid
수량
0.5 mg
제품 유형
Alkyne
분자량
962.63 Da
용해도
DMSO (Dimethylsulfoxide)
화학물질 반응성
Azide
검출 방법
Fluorescent
반응성 그룹
Alkyne
배송 조건
Room Temperature
반응성 부분
Alkyne
라벨 또는 염료
Alexa Fluor™ 594
라벨 유형
Alexa Fluor
색상
Red
제품라인
Alexa Fluor™, Molecular Probes™
구성 및 보관
Store at ≤-20°C, desiccate and protect from light.