Orbitrap™ Ascend Editions Tribrid™ Mass Spectrometer

Exceed experimental expectation and versatility with recommended MultiOmics, Structural Biology, and BioPharma configurations of the Thermo Scientific™ Orbitrap Ascend Editions Tribrid™ Mass Spectrometer. Each Edition provides a tailored configuration of options for each application space, simplifying your decisions and streamlining your research. Characterize even the largest biopharmaceuticals and protein complexes with the Native MS option, which extends the Orbitrap mass range up to m/z 16,000 and new quadrupole isolation up to m/z 8,000. Unlock the potential of alternate fragmentation techniques to decipher the most challenging molecules.

With three unique fit-for-purpose Editions that are tailored for MultiOmics; Structural Biology; and BioPharma application areas, Orbitrap Ascend Editions Tribrid mass spectrometers ensure high-quality data acquisition. Whether you're focused on multiplexed quantitative proteomics, metabolomics, lipidomics or glycomics, small molecule-based pharmaceuticals or biotherapeutics, single-cell or deciphering higher-order protein structures; these instruments are uniquely suited to your needs.

• Native MS option: Orbitrap extended mass range up to m/z 16000 and new quadrupole isolation up to m/z 8000 for improved selectivity and MSⁿ sensitivity of macromolecules.
• PTCR option: Reduce m/z spectrum complexity to enhance proteoform characterization at MS¹ and MS² levels.
• UVPD option: Improved fragmentation for top-down proteomics, oligonucleotides, lipidomics, and other analytes
• Easy-ETD option: Achieve high sequence coverage of proteins, including site localization of labile PTMs.
• EASY-IC ion source option: Obtain sub-1ppm mass accuracy with internal calibration.
• Dual IRMs: Confidently identify more molecules with two ion-routing multiples to increase scan rate and sensitivity.
• Real-Time Library Search: Provides higher confidence identifications for peptide or small molecule analysis using MSⁿ.
• Auto-Ready ion source: Spend less time on instrument setup with a new dedicated source for autocalibration.
• Pre-built method templates: Optimized methods for each Edition system, covering diverse applications.
• Dry-Pump: Environmentally friendly, oil-free dry pump is standard to decrease maintenance while providing leak-free vacuum performance.