BODIPY FL GTP-γ-S binds to GTP-binding proteins. To create this fluorescent nucleotide, the BODIPY FL fluorophore was linked through the γ-thiol of GTP-γ-S. The fluorescence of BODIPY FL GTP-γ-S is quenched ∼90% relative to that of the free dye, but may be recovered on binding to G-proteins. In addition to its potential use for binding studies, the BODIPY FL GTP-γ-S thioether is an important new substrate for Fhit, a member of the histidine triad superfamily of nucleotide-binding proteins.
For Research Use Only. Not for use in diagnostic procedures.
사양
제품 유형Guanosine 5'-O
라벨링 방법Chemical Labeling, Direct Labeling
배송 조건Wet Ice
농도5 mM
라벨 또는 염료BODIPY™ FL
수량50 μL
제품라인BODIPY™
Unit Size50 μl
구성 및 보관
Store in freezer -5°C to -30°C and protect from light.