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The CaptureSelect KappaXP MiniChrom column is designed for bench-scale resin screening, process development, and sample preparation. This pre-packed column is ready to connect and has the following features:
The 10-cm bed height of the 5-mL column allows initial process development on a bench scale.
CaptureSelect KappaXP matrix recognizes the kappa light chain of human antibodies, enabling purification of all Kappa containing Ig’s, Fab, and Fab2 fragments directly from complex sources and feed streams.
Features of this affinity matrix include:
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
Main characteristics