Thermo Scientific Chemicals
Glycylglycine, 99%
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100 g
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500 g
Catalog number A10523.22
also known as A10523-22
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Chemical Identifiers
CAS556-50-3
IUPAC Namehydrogen 2-(2-aminoacetamido)acetic acid chloride
Molecular FormulaC4H9ClN2O3
InChI KeyYHBAZQDEMYQPJL-UHFFFAOYSA-N
SMILES[H+].[Cl-].NCC(=O)NCC(O)=O
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SpecificationsSpecification SheetSpecification Sheet
Assay (Non-aqueous acid-base Titration)≥98.5 to ≤101.5%
Appearance (Color)White
FormCrystals or powder or crystalline powder
Glycylglycine is as a buffering reagent and also used in biochemical research. It is the simplest of all dipeptides and is used as a starting template for preparation of more complex peptides. It is also employed as a practical buffer with a buffering range of 7.5 - 8.9 (at 25°C). Valuable agent for experiments investigating peptide transport and absorption.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Glycylglycine is as a buffering reagent and also used in biochemical research. It is the simplest of all dipeptides and is used as a starting template for preparation of more complex peptides. It is also employed as a practical buffer with a buffering range of 7.5 - 8.9 (at 25°C). Valuable agent for experiments investigating peptide transport and absorption.

Solubility
Soluble in water (132 g/L) at 20°C, and ethanol (slightly solube).

Notes
Store at room temperature. Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. Dr. David A.Leigh, Aden Murphy, Dr. John P.Smart Alexandra M.Z.Slawin. Glycylglycine Rotaxanes—The Hydrogen Bond Directed Assembly of Synthetic Peptide Rotaxanes . Angewandte Chemie International Edition in English. 1997, 36, (7),728-732
  2. Noriko Takuwa; Tadahito Shimada; Hisashi Matsumoto; Takeshi Hoshi. Proton-coupled transport of glycylglycine in rabbit renal brush-border membrane vesicles. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1985, 814, (1),186-190